Introduction Both systemic inflammation and dyslipidemia contribute to osteoarthritis (OA)
development and have been suggested as a possible link between metabolic disease and …

Bone injuries such as fractures are one major cause of morbidities worldwide. A
considerable number of fractures suffer from delayed healing, and the unresolved acute …

类风湿性关节炎是一种可引起机体关节疼痛, 肿胀, 畸形甚至器官损害的自身免疫性疾病.
全球发病普遍, 中国发病率为0.42%, 全球为0.27%. 除关节问题外, 该疾病还会导致患者生活 …

Summary Mycobacterium tuberculosis (Mtb) causes 1.3 million deaths a year. However,
tuberculosis (TB) pathogenesis remains poorly understood and is not fully recapitulated in …

Aging negatively impacts central nervous system function; however, the cellular impact of
aging in the peripheral nervous system remains poorly understood. Aged individuals are …

The incidence of pyrogenic contaminations creates a paramount safety concern in the field
of biotherapeutics, as it compromises the normal well-being of an individual. After exposure …

Neuroimmune interactions across the pain pathway play a predominant role in the
development of neuropathic pain. Previous reports demonstrated that complement driven …

Chronic pain is a disease that existed during cancer treatment for a long time. It has been
reported that interleukin (IL)-1 is involved in the inflammatory response during tumor …

A phenomenon commonly observed across various musculoskeletal (MSK) diseases, such
as osteoarthritis (OA), fibromyalgia syndrome (FMS), and persistent post-surgical pain …