Molecular and antibiofilm approaches to prosthetic joint infection.

A Trampuz, DR Osmon, AD Hanssen… - … Research (1976-2007 …, 2003 - journals.lww.com
The majority of patients with prosthetic joint replacement (arthroplasty) experience dramatic
relief of pain and restoration of satisfactory joint function. In the United States, more than. 5 …

Use of broad range16S rDNA PCR in clinical microbiology

S Sontakke, MB Cadenas, RG Maggi… - Journal of …, 2009 - Elsevier
Broad range 16S rDNA PCR can be used to facilitate the diagnosis of infectious diseases of
bacterial origin by detecting 16S rDNA sequences in patient samples. Post amplification …

Diagnosis and treatment of culture-negative periprosthetic joint infection

GS Goh, J Parvizi - The Journal of Arthroplasty, 2022 - Elsevier
Identification of the causative organism (s) in periprosthetic joint infection (PJI) is a
challenging task. The shortcomings of traditional cultures have been emphasized in recent …

Presence of bacterial DNA and bacterial peptidoglycans in joints of patients with rheumatoid arthritis and other arthritides

IM Van Der Heijden, B Wilbrink… - … : Official Journal of …, 2000 - Wiley Online Library
Objective The continuous presence of bacteria or their degraded antigens in the synovium
may be involved in the pathogenesis of rheumatoid arthritis (RA). The aim of this study was …

Identificación bacteriana mediante secuenciación del ARNr 16S: fundamento, metodología y aplicaciones en microbiología clínica

M del Rosario Rodicio… - … infecciosas y microbiología …, 2004 - Elsevier
La comparación de las secuencias de los ARNr 16S (o de los genes que los codifican)
permite establecer las relaciones filogenéticas existentes entre los organismos procariotas …

Antimicrobial treatment options for granulomatous mastitis caused by Corynebacterium species

HC Dobinson, TP Anderson… - Journal of clinical …, 2015 - Am Soc Microbiol
Corynebacterium species are increasingly recognized as important pathogens in
granulomatous mastitis. Currently, there are no published treatment protocols for …

Poor predictive value of broad-range PCR for the detection of arthroplasty infection in 92 cases

K Panousis, P Grigoris, I Butcher, B Rana… - Acta …, 2005 - Taylor & Francis
Background The diagnosis of prosthetic infection remains a challenge, as no test is 100%
sensitive and 100% specific Recent advances in molecular biology have enabled the …

Identification of pathogenic Leptospira species by conventional or real-time PCR and sequencing of the DNA gyrase subunit B encoding gene

AT Slack, ML Symonds, MF Dohnt, LD Smythe - BMC microbiology, 2006 - Springer
Background Leptospira is the causative genus of the disease, leptospirosis. Species
identification of pathogenic Leptospira in the past was generally performed by either DNA …

Rapid identification of bacterial pathogens using a PCR-and microarray-based assay

AK Järvinen, S Laakso, P Piiparinen, A Aittakorpi… - BMC microbiology, 2009 - Springer
Background During the course of a bacterial infection, the rapid identification of the
causative agent (s) is necessary for the determination of effective treatment options. We …

Reverse transcriptase-PCR analysis of bacterial rRNA for detection and characterization of bacterial species in arthritis synovial tissue

KE Kempsell, CJ Cox, M Hurle, A Wong… - Infection and …, 2000 - Am Soc Microbiol
Onset of rheumatoid arthritis (RA) is widely believed to be preceded by exposure to some
environmental trigger such as bacterial infectious agents. The influence of bacteria on RA …