The in vivo pathomechanics of osteoarthritis (OA) at the knee is described in a framework
that is based on an analysis of studies describing assays of biomarkers, cartilage …

Osteoarthritis (OA) is the most common form of arthritic disease, and a major cause of
disability and impaired quality of life in the elderly. OA is a complex disease of the entire …

Developing effective treatment for osteoarthritis (OA), a prevalent and disabling disease, has
remained a challenge, primarily because of limited understanding of its pathogenesis and …

OBJECTIVE: Osteoarthritis (OA) is the most common form of arthritic disease, and it is a
major cause of disability and impaired quality of life in the elderly. OA is a complex disease …

Despite increasing evidence that subchondral bone contributes to osteoarthritis (OA)
pathogenesis, little is known about local changes in bone structure compared to cartilage …

OBJECTIVE: To characterize the rabbit anterior cruciate ligament transection (ACLT) model
of osteoarthritis (OA) at various stages of disease using high-resolution 3-D medical imaging …

There is growing interest in the role of bone in knee osteoarthritis. Bone is a dynamic organ,
tightly regulated by a multitude of homeostatic controls, including genetic and environmental …

Objective To study 3 body fluids for changes in the levels of 5 biomarkers of cartilage
metabolism during the early phases of experimental osteoarthritis (OA). Methods Twenty …

OBJECTIVE: To investigate the relationship between efficacy of a bisphosphonate, pain and
extent of joint damage in the monosodium iodoacetate (MIA) model of painful degenerative …

OBJECTIVE: To correlate degenerative changes in cartilage and subchondral bone in the
third carpal bone (C3) of Standardbred racehorses with naturally occurring repetitive trauma …