Integrated safety summary of FOCUS 1 and FOCUS 2 trials: phase III randomized, double-blind studies evaluating ceftaroline fosamil for the treatment of patients with …

DR Rank, HD Friedland… - Journal of antimicrobial …, 2011 - academic.oup.com
Objectives Ceftaroline fosamil, the prodrug of the active metabolite ceftaroline, is a broad-
spectrum, parenteral cephalosporin approved for treatment of moderate to severe bacterial …

Ceftaroline fosamil: a cephalosporin with activity against methicillin-resistant Staphylococcus aureus

H Poon, MH Chang, HB Fung - Clinical therapeutics, 2012 - Elsevier
BACKGROUND: Ceftaroline is a cephalosporin with expanded gram-positive activity
recently approved for clinical uses by the US Food and Drug Administration. OBJECTIVE …

Activity of ceftaroline and comparator agents tested against Staphylococcus aureus from patients with bloodstream infections in US medical centres (2009–13)

HS Sader, DJ Farrell, RK Flamm… - Journal of Antimicrobial …, 2015 - academic.oup.com
Objectives The objective of this study was to evaluate the in vitro antimicrobial activity of
ceftaroline and comparator agents tested against Staphylococcus aureus isolates causing …

Use of ceftaroline fosamil in osteomyelitis: CAPTURE study experience

LB Johnson, A Ramani, DJ Guervil - BMC Infectious Diseases, 2019 - Springer
Background Osteomyelitis is often challenging to treat. This analysis examined the clinical
experience of patients with gram-positive osteomyelitis treated with ceftaroline fosamil in the …

High incidence of discontinuations due to adverse events in patients treated with ceftaroline

R Jain, JD Chan, L Rogers, TH Dellit… - … : The Journal of …, 2014 - Wiley Online Library
Study Objective To determine clinical outcomes in patients who received ceftaroline
(Teflaro) 600 mg intravenously every 8 or 12 hours after failing or developing intolerance to …

Methicillin-resistant, vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus infections in solid organ transplantation

C Garzoni, P Vergidis - American Journal of Transplantation, 2013 - amjtransplant.org
Abbreviations: CA-MRSA, community-associated MRSA; CLSI, Clinical and Laboratory
Standards Institute; EARSS, European Antimicrobial Resistance Surveillance System; HA …

Ceftaroline: systematic review of clinical uses and emerging drug resistance

G Abate, G Wang, J Frisby - Annals of Pharmacotherapy, 2022 - journals.sagepub.com
Objective To assess the success rates of off-label uses of ceftaroline for infections caused by
methicillin-resistant Staphylococcus aureus (MRSA) and evaluate emerging ceftaroline …

Review of ceftaroline fosamil microbiology: integrated FOCUS studies

IA Critchley, PB Eckburg, A Jandourek… - Journal of …, 2011 - academic.oup.com
Ceftaroline fosamil, the prodrug form of ceftaroline, is a novel broad-spectrum parenteral
cephalosporin that exhibits antibacterial activity against typical respiratory pathogens such …

New treatments for emerging cystic fibrosis pathogens other than Pseudomonas

V Waters - Current pharmaceutical design, 2012 - ingentaconnect.com
The development of antimicrobial treatments for respiratory pathogens in cystic fibrosis (CF)
has been an integral component to the increased survival of CF patients over the past fifty …

Antibiotic Management of Methicillin-Resistant Staphylococcus aureus–Associated Acute Pulmonary Exacerbations in Cystic Fibrosis

NM Fusco, KA Toussaint… - Annals of …, 2015 - journals.sagepub.com
Objective: To review the treatment of methicillin-resistant Staphylococcus aureus (MRSA)–
associated acute pulmonary exacerbations (APEs) in cystic fibrosis (CF). Data Sources: A …