Interleukins and interferons in mesenchymal stromal stem cell-based gene therapy of cancer

U Švajger, U Kamenšek - Cytokine & Growth Factor Reviews, 2024 - Elsevier
The tumor microenvironment is importantly shaped by various cytokines, where interleukins
(ILs) and interferons (IFNs) shape the balance of immune activity within tumor niche and …

The role of interleukins in HBV infection: A narrative review

K Dimitriadis, S Katelani, M Pappa… - Journal of Personalized …, 2023 - mdpi.com
Hepatitis B virus (HBV) infection is a worldwide medical issue with significant morbidity and
mortality, as it is the main cause of chronic liver disease and hepatocellular carcinoma …

Pemphigus‐und Pemphigoid‐Erkrankungen: Klinik, Diagnostik und Therapie: Pemphigus and pemphigoids: Clinical presentation, diagnosis and therapy

D Didona, MF Schmidt, R Maglie… - JDDG: Journal der …, 2023 - Wiley Online Library
Pemphigus und Pemphigoid sind seltene Autoimmunkrankheiten der Haut mit potenziell
lebensbedrohlichem Verlauf. Autoantikörper gegen epidermale und junktionale …

Cigarette smoke stimulates clonal expansion of Jak2V617F and Tet2-/- cells

G Ramanathan, JH Chen, N Mehrotra, T Trieu… - Frontiers in …, 2023 - frontiersin.org
Introduction Somatic mutations in myeloid growth factor pathway genes, such as JAK2, and
genes involved in epigenetic regulation, such as TET2, in hematopoietic stem cells (HSCs) …

Dysfunction of inflammatory pathways and their relationship with anti-hypothalamic autoantibodies in patients with anorexia nervosa

A Amerio, A Escelsior, E Martino, A Strangio… - Nutrients, 2023 - mdpi.com
Background: Despite several attempts, the etiopathogenesis of anorexia nervosa (AN) is still
unknown. However, the activation of the immune response in neuropsychiatric diseases …

[HTML][HTML] Exploring the Role of PD-1 in the Autoimmune Response: Insights into Its Implication in Systemic Lupus Erythematosus

N Sagrero-Fabela, R Chávez-Mireles… - International Journal of …, 2024 - mdpi.com
Despite advances in understanding systemic lupus erythematosus (SLE), many challenges
remain in unraveling the precise mechanisms behind the disease's development and …

[HTML][HTML] Cut-off values for IL-21 and IL-23 as biochemical markers for pemphigus vulgaris

ZA Al-Hasnawi, ALD Ban - Journal of Medicine and Life, 2023 - ncbi.nlm.nih.gov
Pemphigus vulgaris (PV) is a potentially fatal mucocutaneous autoimmune disease
characterized by severe skin lesions. Interleukin-21 (IL-21) and IL-23 have been linked to …

The role of Interleukin-21 in autoimmune Diseases: Mechanisms, therapeutic Implications, and future directions

AM Shbeer, IA Robadi - Cytokine, 2024 - Elsevier
IL-21 is a multifunctional cytokine that regulates the functional activity of various immune
cells. Initial studies have shown that IL-21 can influence the differentiation, proliferation and …

Coccomyxa subellipsoidea KJ Components Enhance the Expression of Metallothioneins and Th17 Cytokines during Human T Cell Activation

T Seki, S Ohshima, S Komatsu, S Yamada… - Microorganisms, 2024 - mdpi.com
Coccomyxa subellipsoidea KJ (C-KJ) is a green alga with unique immunoregulatory
characteristics. Here, we investigated the mechanism underlying the modification of T cell …

Potential Aspects of the Use of Cytokines in Atopic Dermatitis

M Krupka-Olek, A Bożek, D Aebisher… - Biomedicines, 2024 - mdpi.com
Atopic dermatitis (AD) is an abnormal inflammatory response in the skin to food,
environmental IgE, or non-IgE allergens. This disease belongs to a group of inflammatory …