Soft materials as biological and artificial membranes

S Tang, Z Davoudi, G Wang, Z Xu, T Rehman… - Chemical Society …, 2021 - pubs.rsc.org
The past few decades have seen emerging growth in the field of soft materials for synthetic
biology. This review focuses on soft materials involved in biological and artificial …

Nanoparticles for vaccine and gene therapy: Overcoming the barriers to nucleic acid delivery

LM Mollé, CH Smyth, D Yuen… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Nucleic acid therapeutics can be used to control virtually every aspect of cell behavior and
therefore have significant potential to treat genetic disorders, infectious diseases, and …

Ultrasound-remote selected activation mitophagy for precise treatment of rheumatoid arthritis by two-dimensional piezoelectric nanosheets

B Li, C Yang, M Guo, S Wang, W Peng, Q Guo… - ACS …, 2022 - ACS Publications
Excess reactive oxygen species (ROS) produced by abnormal mitochondria is one of the
critical triggers of rheumatoid arthritis (RA). Existing nanocatalytic therapies can only …

Intracellular delivery of nanocarriers and targeting to subcellular organelles

A Jhaveri, V Torchilin - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Recent trends in drug delivery indicate a steady increase in the use of targeted
therapeutics to enhance the specific delivery of biologically active payloads to diseased …

Power of mitochondrial drug delivery systems to produce innovative nanomedicines

Y Yamada, M Hibino, D Sasaki, J Abe… - Advanced Drug Delivery …, 2020 - Elsevier
Mitochondria carry out various essential functions including ATP production, the regulation
of apoptosis and possess their own genome (mtDNA). Delivering target molecules to this …

Rational designs at the forefront of mitochondria-targeted gene delivery: recent progress and future perspectives

N Yoshinaga, K Numata - ACS Biomaterials Science & …, 2022 - ACS Publications
Mitochondria play an essential role in cellular metabolism and generate energy in cells. To
support these functions, several proteins are encoded in the mitochondrial DNA (mtDNA) …

Nanotechnology inspired tools for mitochondrial dysfunction related diseases

R Wen, B Banik, RK Pathak, A Kumar… - Advanced drug delivery …, 2016 - Elsevier
Mitochondrial dysfunctions are recognized as major factors for various diseases including
cancer, cardiovascular diseases, diabetes, neurological disorders, and a group of diseases …

COVID-19. Pandemic surgery guidance

BLDM Brücher, G Nigri, A Tinelli, J Florencio… - 4 OPEN, 2020 - iris.uniroma1.it
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

Therapeutic approaches to treat mitochondrial diseases:“one-size-fits-all” and “precision medicine” strategies

E Bottani, C Lamperti, A Prigione, V Tiranti, N Persico… - Pharmaceutics, 2020 - mdpi.com
Primary mitochondrial diseases (PMD) refer to a group of severe, often inherited genetic
conditions due to mutations in the mitochondrial genome or in the nuclear genes encoding …

Gene therapy for mitochondrial diseases: Current status and future perspective

A Di Donfrancesco, G Massaro, I Di Meo, V Tiranti… - Pharmaceutics, 2022 - mdpi.com
Mitochondrial diseases (MDs) are a group of severe genetic disorders caused by mutations
in the nuclear or mitochondrial genome encoding proteins involved in the oxidative …