The innate immune response is a rapid response to pathogens or danger signals. It is
precisely activated not only to efficiently eliminate pathogens but also to avoid excessive …

The innate immune system represents the host's first-line defense against pathogens, dead
cells or environmental factors. One of the most important inflammatory pathways is …

Background: Ulcerative colitis (UC) is a chronic recurrent inflammatory bowel disease (IBD).
The conventional drugs for UC may induce severe side effects. Herbal medicine is …

Pathogens or danger signals trigger the immune response. Moderate immune response
activation removes pathogens and avoids excessive inflammation and tissue damage …

Osteoarthritis (OA) is a prevalent joint disease with no effective treatment strategies.
Aberrant mechanical stimuli was demonstrated to be an essential factor for OA …

Aberrant NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) inflammasome
activation in innate immune cells, triggered by diverse cellular danger signals, leads to the …

Gout is a disease caused by uric acid (UA) accumulation in the joints, causing inflammation.
Two UA forms–monosodium urate (MSU) and soluble uric acid (sUA) have been shown to …

Due to its low molecular weight and abundant functional groups, water-soluble lignin (WSL)
is considered as a more potent antioxidant than traditional industrial lignin in biofields …

Necrotizing enterocolitis (NEC), an acute intestinal inflammatory disease of premature
infants, is one of the leading causes of death in neonates. Effective measures for clinical …

Inflammation is a hallmark in many forms of cancer; with colitis-associated colorectal cancer
(CAC) being a progressive intestinal inflammation due to inflammatory bowel disease (IBD) …