[HTML][HTML] Regulated cell death (RCD) in cancer: key pathways and targeted therapies
F Peng, M Liao, R Qin, S Zhu, C Peng, L Fu… - Signal transduction and …, 2022 - nature.com
Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the
form of cell death that can be regulated by a variety of biomacromolecules, which is …
form of cell death that can be regulated by a variety of biomacromolecules, which is …
[HTML][HTML] Pyroptosis: mechanisms and diseases
P Yu, X Zhang, N Liu, L Tang, C Peng… - Signal transduction and …, 2021 - nature.com
Currently, pyroptosis has received more and more attention because of its association with
innate immunity and disease. The research scope of pyroptosis has expanded with the …
innate immunity and disease. The research scope of pyroptosis has expanded with the …
[HTML][HTML] The ZAR1 resistosome is a calcium-permeable channel triggering plant immune signaling
G Bi, M Su, N Li, YU Liang, S Dang, J Xu, M Hu… - Cell, 2021 - cell.com
Nucleotide-binding, leucine-rich repeat receptors (NLRs) are major immune receptors in
plants and animals. Upon activation, the Arabidopsis NLR protein ZAR1 forms a pentameric …
plants and animals. Upon activation, the Arabidopsis NLR protein ZAR1 forms a pentameric …
[HTML][HTML] Structural basis of NINJ1-mediated plasma membrane rupture in cell death
M Degen, JC Santos, K Pluhackova, G Cebrero… - Nature, 2023 - nature.com
Eukaryotic cells can undergo different forms of programmed cell death, many of which
culminate in plasma membrane rupture as the defining terminal event,,,,,–. Plasma …
culminate in plasma membrane rupture as the defining terminal event,,,,,–. Plasma …
[HTML][HTML] Inflammation-related pyroptosis, a novel programmed cell death pathway, and its crosstalk with immune therapy in cancer treatment
In recent decades, chemotherapies targeting apoptosis have emerged and demonstrated
remarkable achievements. However, emerging evidence has shown that chemoresistance is …
remarkable achievements. However, emerging evidence has shown that chemoresistance is …
[HTML][HTML] A novel defined pyroptosis-related gene signature for predicting the prognosis of ovarian cancer
Y Ye, Q Dai, H Qi - Cell death discovery, 2021 - nature.com
Ovarian cancer (OC) is a highly malignant gynaecological tumour that has a very poor
prognosis. Pyroptosis has been demonstrated in recent years to be an inflammatory form of …
prognosis. Pyroptosis has been demonstrated in recent years to be an inflammatory form of …
[HTML][HTML] Programmed cell death tunes tumor immunity
The demise of cells in various ways enables the body to clear unwanted cells. Studies over
the years revealed distinctive molecular mechanisms and functional consequences of …
the years revealed distinctive molecular mechanisms and functional consequences of …
Apoptosis, pyroptosis, and necroptosis—Oh my! The many ways a cell can die
N Ketelut-Carneiro, KA Fitzgerald - Journal of molecular biology, 2022 - Elsevier
Cell death is an essential process in all living organisms and occurs through different
mechanisms. The three main types of programmed cell death are apoptosis, pyroptosis, and …
mechanisms. The three main types of programmed cell death are apoptosis, pyroptosis, and …
[HTML][HTML] The caspase-3/GSDME signal pathway as a switch between apoptosis and pyroptosis in cancer
M Jiang, L Qi, L Li, Y Li - Cell death discovery, 2020 - nature.com
Apoptosis has long been recognized as a mechanism that kills the cancer cells by cytotoxic
drugs. In recent years, studies have proved that pyroptosis can also shrink tumors and inhibit …
drugs. In recent years, studies have proved that pyroptosis can also shrink tumors and inhibit …
[HTML][HTML] Nickel: Human health and environmental toxicology
G Genchi, A Carocci, G Lauria, MS Sinicropi… - International journal of …, 2020 - mdpi.com
Nickel is a transition element extensively distributed in the environment, air, water, and soil.
It may derive from natural sources and anthropogenic activity. Although nickel is ubiquitous …
It may derive from natural sources and anthropogenic activity. Although nickel is ubiquitous …