Inflammasome complexes and their integral receptor proteins have essential roles in
regulating the innate immune response and inflammation at the post-translational level. Yet …

The pervasive application of chimeric antigen receptor (CAR)-based cellular therapies in the
treatment of oncological diseases has long been recognized. However, CAR T cells can …

Abstract Type I interferon (IFN-I) plays crucial roles in the regulation of inflammation and it is
associated with various inflammatory diseases including systemic lupus erythematosus …

Purpose: The aim of the study was to compare the difference in composition between 100%
autologous serum (AS) and 100% platelet-rich plasma (PRP) eye drops and assess their …

Approximately 1% of all patients with Sjögren's syndrome (SS) are children. Unlike the adult
form, in which sicca syndrome is the main presentation, in children, the most common …

Necroptosis is a form of regulated necrotic cell death and has been confirmed to play pivotal
roles in the pathogenesis of multiple autoimmune diseases such as rheumatoid arthritis (RA) …

Sjögren's syndrome is a systemic autoimmune disease characterized by dysfunction of the
affected exocrine glands. Lymphocytic infiltration within the inflamed glands and aberrant B …

Because of their unique capacity for differentiation to a diversity of cell lineages and
immunosuppressive properties, mesenchymal stem cells (MSC) are being looked at as a …

Background Sjögren's syndrome (SS) is a chronic autoimmune disease characterized by
exocrine and extra-glandular symptoms. The literature indicates that SS is an independent …

Primary Sjögren's disease is primarily driven by B-cell activation and is associated with a
high risk of developing non-Hodgkin's lymphoma (NHL). Over the last few decades …