Nonspecific binding—fundamental concepts and consequences for biosensing applications
A Frutiger, A Tanno, S Hwu, RF Tiefenauer… - Chemical …, 2021 - ACS Publications
Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …
through precise control of biomolecules in space and time. Artificial systems such as …
Immunomodulatory effects of probiotics on cytokine profiles
Probiotics confer immunological protection to the host through the regulation, stimulation,
and modulation of immune responses. Researchers have shifted their attention to better …
and modulation of immune responses. Researchers have shifted their attention to better …
An in silico deep learning approach to multi-epitope vaccine design: a SARS-CoV-2 case study
The rampant spread of COVID-19, an infectious disease caused by SARS-CoV-2, all over
the world has led to over millions of deaths, and devastated the social, financial and political …
the world has led to over millions of deaths, and devastated the social, financial and political …
BepiPred‐3.0: Improved B‐cell epitope prediction using protein language models
B‐cell epitope prediction tools are of great medical and commercial interest due to their
practical applications in vaccine development and disease diagnostics. The introduction of …
practical applications in vaccine development and disease diagnostics. The introduction of …
An update on SARS-CoV-2/COVID-19 with particular reference to its clinical pathology, pathogenesis, immunopathology and mitigation strategies
Abstract Coronavirus Disease 2019 (COVID-19), emerged in early December 2019 in China
and became a pandemic situation worldwide by its rapid spread to more than 200 countries …
and became a pandemic situation worldwide by its rapid spread to more than 200 countries …
Atlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profiling
To gain mechanistic insights into the functions and developmental dynamics of tumor-
infiltrated immune cells, especially B-lymphocytes, here we combine single-cell RNA …
infiltrated immune cells, especially B-lymphocytes, here we combine single-cell RNA …
Molecularly imprinted polymers as synthetic antibodies for protein recognition: the next generation
Molecularly imprinted polymers (MIPs) are chemical antibody mimics obtained by
nanomoulding the 3D shape and chemical functionalities of a desired target in a synthetic …
nanomoulding the 3D shape and chemical functionalities of a desired target in a synthetic …
Immunoinformatics and vaccine development: an overview
AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …
saved several lives, reduced treatment costs and raised the quality of animal and human …
Structure-based drug designing and immunoinformatics approach for SARS-CoV-2
The prevalence of respiratory illness caused by the novel SARS-CoV-2 virus associated with
multiple organ failures is spreading rapidly because of its contagious human-to-human …
multiple organ failures is spreading rapidly because of its contagious human-to-human …
A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding
Antibody-antigen binding relies on the specific interaction of amino acids at the paratope-
epitope interface. The predictability of antibody-antigen binding is a prerequisite for de novo …
epitope interface. The predictability of antibody-antigen binding is a prerequisite for de novo …