Sesquiterpernes are natural compounds widely distributed in plants rich in essential oils;
among these compounds, α-humulene and its isomers stand out for their multiple …

Lung adenocarcinoma (LUAD) is the most frequent subtype of lung cancer worldwide.
However, the survival rate of LUAD patients remains low. N6-methyladenosine (m 6 A) and …

Simple Summary This review discusses new findings for the roles of TNFR1 and TNFR2 in
the development of aggressive lung squamous cell carcinoma and lung adenocarcinoma by …

Tumor necrosis factor superfamily (TNFSF) resistance contributes to the development and
progression of tumors and resistance to various cancer therapies. Tumor-intrinsic alterations …

The potent pro-inflammatory cytokine tumor necrosis factor α (TNFα) has been connected to
cancer progression and treatment ever since its discovery as a major factor contributing to …

Background Immunotherapy is significantly revolutionizing cancer treatment and
demonstrating promising efficacy in gastric cancer (GC) patients. However, only a subset of …

MAPK pathway sparkles with RTK activation, passes through subsequent downstream RAS-
RAF-MEK-ERK signaling cascades, with consequent direct and indirect CDK4/6 signaling …

Background Detection of circulating tumour DNA (ctDNA) in biological fluids is a minimally
invasive alternative to tissue biopsy for therapy monitoring. Cytokines are released in the …

Globally, lung cancer remains one of the leading causes of cancer-related mortality,
warranting the exploration of novel and effective therapeutic approaches. Soy-fermented …

Simple Summary NSCLC accounts for approximately 84% of lung malignancies and the
clinical application of ICIs provides a novel and promising strategy. However, approximately …