Enterotoxigenic Escherichia coli: intestinal pathogenesis mechanisms and colonization resistance by gut microbiota

Y Zhang, P Tan, Y Zhao, X Ma - Gut Microbes, 2022 - Taylor & Francis
Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea in children and
travelers in developing countries. ETEC is characterized by the ability to produce major …

[HTML][HTML] Review of Newly Identified Functions Associated With the Heat-Labile Toxin of Enterotoxigenic Escherichia coli

Q Duan, P Xia, R Nandre, W Zhang… - Frontiers in cellular and …, 2019 - frontiersin.org
Heat-labile toxin (LT) is a well-characterized powerful enterotoxin produced by
enterotoxigenic Escherichia coli (ETEC). This toxin is known to contribute to diarrhea in …

[HTML][HTML] Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis

MT Ren, ML Gu, XX Zhou, MS Yu, HH Pan… - World Journal of …, 2019 - ncbi.nlm.nih.gov
BACKGROUND Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD+)-dependent
protein deacetylase that is involved in various diseases, including cancers, metabolic …

[HTML][HTML] Tong-Xie-Yao-Fang alleviates diarrhea-predominant irritable bowel syndrome in rats via the GCN2/PERK-eIF2α-ATF4 signaling pathway

M Zhang, Y Zheng, X Li, H Wu, P Liu, K Zhang, Z Shi… - Phytomedicine, 2022 - Elsevier
Background Diarrhea-predominant irritable bowel syndrome (IBS-D) is a common functional
gastrointestinal disease. Tong-Xie-Yao-Fang (TXYF), the traditional Chinese herbal …

A new insight into fluoride induces cardiotoxicity in chickens: Involving the regulation of PERK/IRE1/ATF6 pathway and heat shock proteins

L Hou, H Dong, E Zhang, H Lu, Y Zhang, H Zhao… - Toxicology, 2024 - Elsevier
Fluorosis poses a significant threat to human and animal health and is an urgent public
safety concern in various countries. Subchronic exposure to fluoride has the potential to …

Reactive oxygen species in modulating intestinal stem cell dynamics and function

A Nath, P Chakrabarti, S Sen, A Barui - Stem Cell Reviews and Reports, 2022 - Springer
Frequent exposure to mechanistic damages, pathological ingression, and chronic
inflammation leads to recurrent cell death in the gut epithelium. Intestinal stem cells (ISCs) …

[HTML][HTML] Daidzein protects Caco-2 cells against lipopolysaccharide-induced intestinal epithelial barrier injury by suppressing PI3K/AKT and P38 pathways

B Zhang, X Wei, M Ding, Z Luo, X Tan, Z Zheng - Molecules, 2022 - mdpi.com
The intestinal epithelium provides an important barrier against bacterial endotoxin
translocation, which can regulate the absorption of water and ions. The disruption of …

Impaired intestinal stem cell activity in ETEC infection: enterotoxins, cyclic nucleotides, and Wnt signaling

L Ren, J Zhou, S Liang, X Wang - Archives of Toxicology, 2022 - Springer
Enterotoxigenic Escherichia coli (ETEC) in humans and animals colonizes the intestine and
thereafter secrets heat-stable enterotoxin (ST) with or without heat-labile enterotoxin (LT) …

Generation of Porcine Angiogenin 4-Expressing Pichia pastoris and Its Protection against Intestinal Inflammatory Injury

S Xu, S Chen, Y Liu, X Jia, X Jiang, L Che… - Journal of Agricultural …, 2023 - ACS Publications
Antimicrobial peptides have been extensively studied as potential alternatives to antibiotics.
Porcine angiogenin 4 (pANG4) is a novel antimicrobial peptide in the angiogenin (ANG) …

[HTML][HTML] Agrobacterium sp. ZX09 β-Glucan Attenuates Enterotoxigenic Escherichia coli-Induced Disruption of Intestinal Epithelium in Weaned Pigs

Y Zhou, Y Luo, B Yu, P Zheng, J Yu, Z Huang… - International Journal of …, 2022 - mdpi.com
To explore the protective effect of dietary β-glucan (BGL) supplementation on intestinal
epithelium exposure to enterotoxigenic Escherichia coli (ETEC), thirty-two weaned pigs …