Interest in the contribution of changes in lung development during early life to subsequent
respiratory morbidity is increasing. Most evidence of an association between adverse …

There is increasing evidence that chronic obstructive pulmonary disease (COPD) is not
simply a disease of old age that is largely restricted to heavy smokers, but may be …

ABSTRACT A large number of animal studies and human observational studies suggest a
positive relationship between vitamin A status and lung function. Depletion of vitamin A from …

Alveolarization in humans and nonhuman primates begins during prenatal development.
Advances in stereological counting techniques allow accurate assessment of alveolar …

Despite significant improvements in the care and survival of extremely premature infants,
BPD remains a major clinical problem. Although efforts should remain focused on the …

Bronchopulmonary dysplasia (BPD), a chronic lung disease of infancy, is characterized by
arrested alveolar development. Pulmonary angiogenesis, mediated by the vascular …

In contrast to many other organs, a significant portion of lung development occurs after birth
during alveolarization, thus rendering the lung highly susceptible to injuries that may disrupt …

In developed countries most preterm births occur between 34 and 37 weeks' gestation.
Deliveries during this 'late preterm'period are increasing and, since even mild prematurity is …

Background and Aims Infants with Down syndrome (DS) or Trisomy 21, are at high risk for
developing pulmonary arterial hypertension (PAH), but mechanisms that increase …

The airway epithelium regulates responses to aeroallergens, acting as a physical and
immunological barrier. In asthma, epithelial barrier function and the expression of adherens …