Crotoxin, the main toxin of South American rattlesnake (Crotalus durissus terrificus) venom,
was the first snake venom protein to be purified and crystallized. Crotoxin is a heterodimeric …

The emergence of antibiotic resistance drives an essential race against time to reveal new
molecular structures capable of addressing this alarming global health problem. Snake …

Some proteins present in snake venom possess enzymatic activities, such as phospholipase
A2 and l-amino acid oxidase. In this study, we verify the action of the Bothrops marajoensis …

As polyphenolic compounds isolated from plants extracts, flavonoids have been applied to
various pharmaceutical uses in recent decades due to their anti-inflammatory, cancer …

An increasing problem in the field of health protection is the emergence of drug-resistant
and multi-drug-resistant bacterial strains. They cause a number of infections, including …

Basic phospholipase A2 was identified from the venom of the eastern diamondback
rattlesnake. The Crotalus adamanteus toxin-II (CaTx-II) induced bactericidal effects (7.8 …

A new PLA2 (Cdcum6) from crotoxin complex of Colombian Crotalus durissus cumanensis
rattlesnake was purified using molecular exclusion chromatography and RP-HPLC. The …

In this study, we compared the anti-leishmanial activity of three crotalic venoms (Crotalus
durissus terrificus–Cdt, Crotalus durissus cascavella–Cdca, and Crotalus durissus …

The majority of snake venom phospholipases A2 (svPLA2s) are toxic and induce a wide
spectrum of biological effects. They are cysteine-rich proteins that contain 119-134 amino …

In accidents involving Crotalus snakes, the crotoxin complex (CTX) plays lethal action due to
its neurotoxic activity. On the other hand, CTX have potential biotechnological application …