[HTML][HTML] Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis
RF Little, C Hertweck - Natural Product Reports, 2022 - pubs.rsc.org
Review covering up to mid-2021 The structure of polyketide and non-ribosomal peptide
natural products is strongly influenced by how they are released from their biosynthetic …
natural products is strongly influenced by how they are released from their biosynthetic …
[HTML][HTML] The architectures of iterative type I PKS and FAS
DA Herbst, CA Townsend, T Maier - Natural product reports, 2018 - pubs.rsc.org
Covering: up to mid of 2018 Type I fatty acid synthases (FASs) are giant multienzymes
catalyzing all steps of the biosynthesis of fatty acids from acetyl-and malonyl-CoA by iterative …
catalyzing all steps of the biosynthesis of fatty acids from acetyl-and malonyl-CoA by iterative …
Genomes to natural products prediction informatics for secondary metabolomes (PRISM)
MA Skinnider, CA Dejong, PN Rees… - Nucleic acids …, 2015 - academic.oup.com
Microbial natural products are an invaluable source of evolved bioactive small molecules
and pharmaceutical agents. Next-generation and metagenomic sequencing indicates …
and pharmaceutical agents. Next-generation and metagenomic sequencing indicates …
Monascus secondary metabolites: production and biological activity
P Patakova - Journal of Industrial Microbiology and …, 2013 - academic.oup.com
The genus Monascus, comprising nine species, can reproduce either vegetatively with
filaments and conidia or sexually by the formation of ascospores. The most well-known …
filaments and conidia or sexually by the formation of ascospores. The most well-known …
Navigating the fungal polyketide chemical space: from genes to molecules
The iterative type I polyketide synthases (IPKSs) are central to the biosynthesis of an
enormously diverse array of natural products in fungi. These natural products, known as …
enormously diverse array of natural products in fungi. These natural products, known as …
New insights into the formation of fungal aromatic polyketides
JM Crawford, CA Townsend - Nature Reviews Microbiology, 2010 - nature.com
Fungal aromatic polyketides constitute a large family of bioactive natural products and are
synthesized by the non-reducing group of iterative polyketide synthases (PKSs). Their …
synthesized by the non-reducing group of iterative polyketide synthases (PKSs). Their …
Biosynthesis of fusarubins accounts for pigmentation of Fusarium fujikuroi perithecia
Fusarium fujikuroi produces a variety of secondary metabolites, of which polyketides form
the most diverse group. Among these are the highly pigmented naphthoquinones, which …
the most diverse group. Among these are the highly pigmented naphthoquinones, which …
[HTML][HTML] Structural enzymology of iterative type I polyketide synthases: various routes to catalytic programming
J Wang, Z Deng, J Liang, Z Wang - Natural Product Reports, 2023 - pubs.rsc.org
Time span of literature covered: up to mid-2023 Iterative type I polyketide synthases (iPKSs)
are outstanding natural chemists: megaenzymes that repeatedly utilize their catalytic …
are outstanding natural chemists: megaenzymes that repeatedly utilize their catalytic …
Illuminating the Diversity of Aromatic Polyketide Synthases in Aspergillus nidulans
Genome sequencing has revealed that fungi have the ability to synthesize many more
natural products (NPs) than are currently known, but methods for obtaining suitable …
natural products (NPs) than are currently known, but methods for obtaining suitable …
Recent advances in the identification of biosynthetic genes and gene clusters of the polyketide-derived pathways for anthraquinone biosynthesis and biotechnological …
NK Mund, E Čellárová - Biotechnology Advances, 2023 - Elsevier
Natural anthraquinones are represented by a large group of compounds. Some of them are
widespread across the kingdoms, especially in bacteria, fungi and plants, while the others …
widespread across the kingdoms, especially in bacteria, fungi and plants, while the others …