[HTML][HTML] Endothelial cell dysfunction and nonalcoholic fatty liver disease (NAFLD): A concise review

N Nasiri-Ansari, T Androutsakos, CM Flessa, I Kyrou… - Cells, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide. It is strongly associated with obesity, type 2 diabetes (T2DM), and other …

Causes and metabolic consequences of fatty liver

N Stefan, K Kantartzis, HU Häring - Endocrine reviews, 2008 - academic.oup.com
Type 2 diabetes and cardiovascular disease represent a serious threat to the health of the
population worldwide. Although overall adiposity and particularly visceral adiposity are …

[HTML][HTML] The organoid cell atlas

C Bock, M Boutros, JG Camp, L Clarke, H Clevers… - Nature …, 2021 - nature.com
To the Editor—Human organoids hold tremendous potential for biomedical applications 1–3
(Fig. 1a, b). These three-dimensional structures of cultured cells recapitulate important …

[PDF][PDF] Hepatoprotective effects of the dual peroxisome proliferator‐activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease …

B Staels, A Rubenstrunk, B Noel, G Rigou… - …, 2013 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) covers a spectrum of liver damage ranging from
simple steatosis to nonalcoholic steatohepatitis (NASH), fibrosis, and cirrhosis. To date, no …

[HTML][HTML] Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis [S]

DM Shih, Z Wang, R Lee, Y Meng, N Che… - Journal of lipid …, 2015 - ASBMB
We performed silencing and overexpression studies of flavin containing monooxygenase
(FMO) 3 in hyperlipidemic mouse models to examine its effects on trimethylamine N-oxide …

Inflammatory markers and incident heart failure risk in older adults: the Health ABC (Health, Aging, and Body Composition) study

A Kalogeropoulos, V Georgiopoulou, BM Psaty… - Journal of the American …, 2010 - jacc.org
Objectives: The purpose of this study was to evaluate the association between inflammation
and heart failure (HF) risk in older adults. Background: Inflammation is associated with HF …

Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors

MJ Chapman, W Le Goff, M Guerin… - European heart …, 2010 - academic.oup.com
Subnormal plasma levels of high-density lipoprotein cholesterol (HDL-C) constitute a major
cardiovascular risk factor; raising low HDL-C levels may therefore reduce the residual …

The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in patients with dyslipidemia

JC Fruchart, F Sacks, MP Hermans, G Assmann… - The American journal of …, 2008 - Elsevier
Despite achieving targets for low-density lipoprotein (LDL) cholesterol, blood pressure, and
glycemia in accordance with current standards of care, patients with dyslipidemia remain at …

Roles of PPARs in NAFLD: potential therapeutic targets

A Tailleux, K Wouters, B Staels - … et Biophysica Acta (BBA)-Molecular and …, 2012 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence
due to the obesity epidemic. Hence, NAFLD represents a rising threat to public health …

[HTML][HTML] PM2.5-induced oxidative stress increases intercellular adhesion molecule-1 expression in lung epithelial cells through the IL-6/AKT/STAT3/NF-κB-dependent …

CW Liu, TL Lee, YC Chen, CJ Liang, SH Wang… - Particle and fibre …, 2018 - Springer
Background Epidemiological studies have shown that ambient air pollution is closely
associated with increased respiratory inflammation and decreased lung function. Particulate …