Simple Summary Inflammation is assessed as a hallmark of cancer and it is now widely
recognized that there exists a direct causal link between inflammation and tumors. Among …

Proteases are signaling molecules that specifically control cellular functions by cleaving
protease-activated receptors (PARs). The four known PARs are members of the large family …

In conjunction with the classical functions of regulating intestinal, bone, and kidney calcium
and phosphorus absorption, as well as bone mineralization of vitamin D, the population …

Because of profound effects observed in carcinogenesis, prostaglandins (PGs),
prostaglandin-endoperoxide synthases, and PG receptors are implicated in cancer …

Therapeutic resistance has been and remains to be the major challenge in developing
successful treatments for different cancers and therefore, understanding the underlying …

Background Metabolic reprogramming is one of the hallmarks of cancer cells. The pentose
phosphate pathway (PPP), a branch of glycolysis, is an important metabolic pathway for the …

Non-small-cell lung cancer (NSCLC), a main subtype of lung cancer, is one of the most
common causes of cancer death in men and women worldwide. Circulating tumor DNA …

Previous studies have reported that PID2, which encodes a B‐lectin receptor‐like kinase, is
a key gene in the resistance of rice to Magnaporthe oryzae strain ZB15. However, the PID2 …

Simple Summary Inflammation is the biological response of the body to damaging and toxic
stimuli, and is a positive event that evolves with the resolution of critical events (acute …

Background Drug–drug interactions (DDIs) pose new challenges beyond traditional
pharmacodynamics in the context of optimizing the treatment options with immune …