Neurological and neurodegenerative diseases, particularly those related to aging, are on
the rise, but drug therapies are rarely curative. Functional disorders and the organic …

Ferroptosis is a form of cell death that is distinguished from other types of death for its
peculiar characteristics of death regulated by iron accumulation, increase in ROS, and lipid …

Globally, millions of individuals are impacted by neurodegenerative disorders including
Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD) …

Ferroptosis is a type of programmed cell death that differs from apoptosis, autophagy, and
necrosis and is related to several physio-pathological processes, including tumorigenesis …

Aging is a pathophysiological process that causes a gradual and permanent reduction in all
biological system functions. The phenomenon is caused by the accumulation of …

Neurodegenerative diseases represent a pressing global health challenge, and the
identification of novel mechanisms underlying their pathogenesis is of utmost importance …

Parkinson's disease (PD) is recognized as a degenerative and debilitating
neurodegenerative disorder. The novel protective role of icariside II (ICS II) as a plant …

Osteoarthritis (OA) is a prevalent joint degenerative disease, resulting in a significant
societal burden. However, there is currently a lack of effective treatment option available …

Lead (Pb), a pervasive and ancient toxic heavy metal, continues to pose significant
neurological health risks, particularly in regions such as Southeast Asia. While previous …

Oxidative stress and inflammation are crucial factors contributing to the occurrence and
development of vascular dementia (VD). In a previous study, we demonstrated that …