Carbohydrate-based macromolecular biomaterials

L Su, Y Feng, K Wei, X Xu, R Liu, G Chen - Chemical Reviews, 2021 - ACS Publications
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

Human milk oligosaccharides: every baby needs a sugar mama

L Bode - Glycobiology, 2012 - academic.oup.com
Human milk oligosaccharides (HMOs) are a family of structurally diverse unconjugated
glycans that are highly abundant in and unique to human milk. Originally, HMOs were …

Attenuated interferon and proinflammatory response in SARS-CoV-2–infected human dendritic cells is associated with viral antagonism of STAT1 phosphorylation

D Yang, H Chu, Y Hou, Y Chai, H Shuai… - The Journal of …, 2020 - academic.oup.com
Clinical manifestations of coronavirus disease 2019 (COVID-19) vary from asymptomatic
virus shedding, nonspecific pharyngitis, to pneumonia with silent hypoxia and respiratory …

Antiviral polymers: past approaches and future possibilities

RH Bianculli, JD Mase, MD Schulz - Macromolecules, 2020 - ACS Publications
Treating a viral disease is no simple feat. Drug resistance, latent reservoirs in the body,
emerging novel viruses, and a frequent lack of specific treatments all complicate antiviral …

HIV infection

SG Deeks, J Overbaugh, A Phillips… - Nature reviews Disease …, 2015 - nature.com
More than 75 million people worldwide have been infected with human immunodeficiency
virus (HIV), and there are now approximately 37 million individuals living with the infection …

Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 …

GD Tomaras, NL Yates, P Liu, L Qin, GG Fouda… - Journal of …, 2008 - Am Soc Microbiol
ABSTRACT A window of opportunity for immune responses to extinguish human
immunodeficiency virus type 1 (HIV-1) exists from the moment of transmission through …

C-type lectin receptors in antiviral immunity and viral escape

M Bermejo-Jambrina, J Eder, LC Helgers… - Frontiers in …, 2018 - frontiersin.org
C-type lectin receptors (CLRs) are important pattern recognition receptors involved in
recognition and induction of adaptive immunity to pathogens. Certain CLRs play an …

Setting the stage: host invasion by HIV

F Hladik, MJ McElrath - Nature Reviews Immunology, 2008 - nature.com
For more than two decades, HIV has infected millions of people worldwide each year
through mucosal transmission. Our knowledge of how HIV secures a foothold at both the …

Human milk oligosaccharides: prebiotics and beyond

L Bode - Nutrition reviews, 2009 - academic.oup.com
Human milk oligosaccharides (HMO) are complex glycans that are present at very high
concentrations in human milk but not in infant formula. The significant energy expended by …

Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection

SW Kazer, TP Aicher, DM Muema, SL Carroll… - Nature medicine, 2020 - nature.com
Cellular immunity is critical for controlling intracellular pathogens, but individual cellular
dynamics and cell–cell cooperativity in evolving human immune responses remain poorly …