[HTML][HTML] Cellular mitophagy: mechanism, roles in diseases and small molecule pharmacological regulation
Y Lu, Z Li, S Zhang, T Zhang, Y Liu, L Zhang - Theranostics, 2023 - ncbi.nlm.nih.gov
Cellular mitophagy means that cells selectively wrap and degrade damaged mitochondria
through an autophagy mechanism, thus maintaining mitochondria and intracellular …
through an autophagy mechanism, thus maintaining mitochondria and intracellular …
[HTML][HTML] Mitochondrial adaptation in cancer drug resistance: prevalence, mechanisms, and management
Drug resistance represents a major obstacle in cancer management, and the mechanisms
underlying stress adaptation of cancer cells in response to therapy-induced hostile …
underlying stress adaptation of cancer cells in response to therapy-induced hostile …
In response to precision medicine: Current subcellular targeting strategies for cancer therapy
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …
increasing attention, bringing great opportunities for clinical application. Here, two targeting …
Cuproptosis: Harnessing transition metal for cancer therapy
Transition metal elements, such as copper, play diverse and pivotal roles in oncology. They
act as constituents of metalloenzymes involved in cellular metabolism, function as signaling …
act as constituents of metalloenzymes involved in cellular metabolism, function as signaling …
The dawn of a new era: targeting the “undruggables” with antibody-based therapeutics
The high selectivity and affinity of antibodies toward their antigens have made them a highly
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …
Mitochondria-targeting Cu3VS4 nanostructure with high copper ionic mobility for photothermoelectric therapy
Y Dong, S Dong, C Yu, J Liu, S Gai, Y Xie, Z Zhao… - Science …, 2023 - science.org
Thermoelectric therapy has emerged as a promising treatment strategy for oncology, but it is
still limited by the low thermoelectric catalytic efficiency at human body temperature and the …
still limited by the low thermoelectric catalytic efficiency at human body temperature and the …
[HTML][HTML] Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology
Cancer is a major threat to human health. Among various treatment methods, precision
therapy has received significant attention since the inception, due to its ability to efficiently …
therapy has received significant attention since the inception, due to its ability to efficiently …
Theranostic fluorescent probes
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
Dynamic assembly of DNA nanostructures in living cells for mitochondrial interference
F Li, Y Liu, Y Dong, Y Chu, N Song… - Journal of the American …, 2022 - ACS Publications
Constructing artificial dynamic architectures inside cells to rationally interfere with organelles
is emerging as an efficient strategy to regulate the behaviors and fate of cells, thus providing …
is emerging as an efficient strategy to regulate the behaviors and fate of cells, thus providing …
Unraveling mitochondria‐targeting reactive oxygen species modulation and their implementations in cancer therapy by nanomaterials
H Peng, F Yao, J Zhao, W Zhang, L Chen, X Wang… - …, 2023 - Wiley Online Library
Functional subcellular organelle mitochondria are emerging as a crucial player and driver of
cancer. For maintaining the sites of cellular respiration, mitochondria experience production …
cancer. For maintaining the sites of cellular respiration, mitochondria experience production …