Alzheimer's disease (AD) is known as the most fatal chronic neurodegenerative disease in
adults along with progressive loss of memory and other cognitive function disorders. Cyclin …

The neuropathological hallmarks of Alzheimer's disease (AD) include senile plaques of β-
amyloid (Aβ) peptides (a cleavage product of the Amyloid Precursor Protein, or APP) and …

Slow paced breathing via heart rate variability (HRV) biofeedback stimulates vagus-nerve
pathways that counter noradrenergic stress and arousal pathways that can influence …

Although previously considered entirely reversible, general anaesthesia is now being
viewed as a potentially significant risk to cognitive performance at both extremes of age. A …

The mechanisms that confer cognitive resilience to Alzheimer's Disease (AD) are not fully
understood. Here, we describe a neural circuit mechanism underlying this resilience in a …

Background There is a growing interest in the involvement of anesthetic agents in the
etiology of postoperative cognitive dysfunction. Recent animal studies suggest that acute …

Extensive tau-immunoreactive neurons and glial cells associated with chronic traumatic
encephalopathy (CTE) have been documented in the brains of some professional athletes …

In Alzheimer's disease (AD) and other tauopathies, the microtubule-associated protein tau
can undergo aberrant hyperphosphorylation potentially leading to the development of …

Alzheimer's disease (AD) is the most common form of dementia and remains a growing
worldwide health problem. As life expectancy continues to increase, the number of AD …

Objectives To evaluate the associations between anesthesia and dementia or Alzheimer's
disease (AD) risk using prospectively collected data. Design Cohort study. Participants …