Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …

Polycystic ovary syndrome (PCOS) is an endocrine-gynecology disorder affecting many
women of childbearing age. Although a part of the involved mechanism in PCOS occurrence …

The prevalence of type 2 diabetes mellitus is increasing in both sexes, but men are usually
diagnosed at a younger age and lower body fat mass than women. Worldwide, an estimated …

Glucagon like peptide-1 (GLP-1) is an incretin secretory molecule. GLP-1 receptor agonists
(GLP-1RAs) are widely used in the treatment of type 2 diabetes (T2DM) due to their …

As the gut microbiota exerts various effects on the intestinal milieu which influences distant
organs and pathways, it is considered to be a full-fledged endocrine organ. The microbiota …

Despite its position as the first-line drug for treatment of type 2 diabetes mellitus, the
mechanisms underlying the plasma glucose level-lowering effects of metformin (1, 1 …

Polycystic ovary syndrome (PCOS) is a heterogeneous disorder characterized by
hyperandrogenism and chronic anovulation. Depending on diagnostic criteria, 6% to 20% of …

Polycystic ovary syndrome (PCOS) is a unification of endocrine and metabolic disorders and
has become immensely prevalent among women of fertile age. The prime organ affected in …

Context Obesity is responsible for an increased risk of sub-fecundity and infertility. Obese
women show poorer reproductive outcomes regardless of the mode of conception, and …

Per-and poly-fluoroalkyl substances (PFAS) are widespread environmental contaminants
frequently detected in drinking water supplies worldwide that have been linked to a variety of …