Bioactive compounds derived from herbal medicinal plants modulate various therapeutic
targets and signaling pathways associated with cardiovascular diseases (CVDs), the world's …

Atherosclerosis, a chronic systemic inflammatory condition, is implicated in most
cardiovascular ischemic events. The pathophysiology of atherosclerosis involves various …

Acute myocardial infarction (AMI), a critical manifestation of coronary heart disease, presents
a complex and not entirely understood etiology. This study investigates the potential role of …

Cardiovascular diseases represent a significant worldwide problem, jeopardizing
individuals' physical and mental wellbeing as well as their quality of life as a result of their …

Abstract Aims Endothelial-mesenchymal transition (EndMT) is a crucial pathological process
contributing to cardiac fibrosis. Bradykinin has been found to protect the heart against …

Atherosclerosis (AS) is a severe vascular disease that results in millions of cases of mortality
each year. The development of atherosclerosis is associated with vascular structural lesions …

Heart failure with preserved ejection fraction (HFpEF) has an estimated incidence rate of
approximately 27 cases per 10,000 person-year [1]. Furthermore, the prevalence of HFpEF …

Lysine crotonylation is a newly identified posttranslational modification that is different from
the widely studied lysine acetylation in structure and function. In the last dozen years, great …

The purpose of our study was to investigate the role of TGF-β1 in the endothelial-to-
mesenchymal transition (EndoMT) and fibrosis in high glucose (HG)-treated human retinal …

Introduction: In the development of atherosclerosis, the remodeling of blood vessels is a key
process involving plaque formation and rupture. So far, most reports mainly believe that …