Recent advances in electrochemical biosensors for the detection of Aβ42, a biomarker for Alzheimer disease diagnosis

M Ding, S Ding, D Du, X Wang, X Hu, P Guan… - TrAC Trends in …, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a long latency in
the" prodromal" stage, for which there are currently no effective treatments. It is generally …

The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications

Y Aman, J Frank, SH Lautrup, A Matysek, Z Niu… - Mechanisms of ageing …, 2020 - Elsevier
Nicotinamide adenine dinucleotide (NAD+) is an important natural molecule involved in
fundamental biological processes, including the TCA cycle, OXPHOS, β-oxidation, and is a …

[HTML][HTML] Harmonizing functional connectivity reduces scanner effects in community detection

AA Chen, D Srinivasan, R Pomponio, Y Fan… - NeuroImage, 2022 - Elsevier
Community detection on graphs constructed from functional magnetic resonance imaging
(fMRI) data has led to important insights into brain functional organization. Large studies of …

Classification of adolescent major depressive disorder via static and dynamic connectivity

B Sen, KR Cullen, KK Parhi - IEEE Journal of Biomedical and …, 2020 - ieeexplore.ieee.org
This paper introduces an approach for classifying adolescents suffering from MDD using
resting-state fMRI. Accurate diagnosis of MDD involves interviews with adolescent patients …

Iterative filtering decomposition based early dementia diagnosis using EEG with cognitive tests

N Sharma, MH Kolekar, K Jha - IEEE Transactions on Neural …, 2020 - ieeexplore.ieee.org
Objective: There has been a constant increase in life expectancy with the advancement of
modern medicine. Likewise, dementia has also increased and projected to elevate in the …

Dysregulated Fc gamma receptor–mediated phagocytosis pathway in Alzheimer's disease: network-based gene expression analysis

YH Park, A Hodges, SL Risacher, K Lin, JW Jang… - Neurobiology of …, 2020 - Elsevier
Transcriptomics has become an important tool for identification of biological pathways
dysregulated in Alzheimer's disease (AD). We performed a network-based gene expression …

Sensing alzheimer's disease utilizing au electrode by controlling nanorestructuring

CH Hsu, AK Gupta, A Purwidyantri, BA Prabowo… - Chemosensors, 2022 - mdpi.com
This paper reports the development of Alzheimer's disease (AD) sensor through early
detection of amyloid-beta (Aβ)(1–42) using simple nanorestructuring of Au sheet plate by …

Brain network classification based on dynamic graph attention information bottleneck

C Dong, D Sun - Computer Methods and Programs in Biomedicine, 2024 - Elsevier
Abstract Background and Objectives Graph neural networks (GNN) have demonstrated
remarkable encoding capabilities in the context of brain network classification tasks. They …

A miniaturized hydrogel-based in vitro model for dynamic culturing of human cells overexpressing beta-amyloid precursor protein

M Tunesi, L Izzo, I Raimondi… - Journal of tissue …, 2020 - journals.sagepub.com
Recent findings have highlighted an interconnection between intestinal microbiota and the
brain, referred to as microbiota–gut–brain axis, and suggested that alterations in microbiota …

MOINER: a novel multiomics early integration framework for biomedical classification and biomarker discovery

W Zhang, M Mou, W Hu, M Lu, H Zhang… - Journal of Chemical …, 2024 - ACS Publications
In the context of precision medicine, multiomics data integration provides a comprehensive
understanding of underlying biological processes and is critical for disease diagnosis and …