Trauma-and disease-related skeletal defects and illnesses are plaguing millions of people
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …

Surface curvature both emerges from, and influences the behavior of, living objects at length
scales ranging from cell membranes to single cells to tissues and organs. The relevance of …

Fibroblasts are cells present throughout the human body that are primarily responsible for
the production and maintenance of the extracellular matrix (ECM) within the tissues. They …

Abstract Triply Periodic Minimal Surface (TPMS) scaffolds have recently received
considerable attention because of their potentials to be used as internal structures of …

Optimization of porous titanium alloy scaffolds designed for orthopedic implants requires
balancing mechanical properties and osseointegrative performance. The tradeoff between …

Selective laser melting is a promising additive manufacturing technology for manufacturing
porous metallic bone scaffolds. Bone repair requires scaffolds that meet various mechanical …

The early development of many organisms involves the folding of cell monolayers, but this
behaviour is difficult to reproduce in vitro; therefore, both mechanistic causes and effects of …

Partially due to the unavailability of ideal bone substitutes, the treatment of large bony
defects remains one of the most important challenges of orthopedic surgery. Additively …

Spatial dimension of pores and interconnection in macroporous scaffolds is of particular
importance in facilitating endogenous cell migration and bone tissue ingrowth. However, it is …

Additive manufacturing (AM, also known as 3D printing) is an advanced manufacturing
technique that has enabled progress in the design and fabrication of customised or patient …