Objective imaging diagnostics for dry eye disease

SB Han, YC Liu, K Mohamed-Noriega… - Journal of …, 2020 - Wiley Online Library
Traditional diagnostic tests for dry eye disease (DED), such as fluorescein tear film break‐up
time and the Schirmer test, are often associated with poor reproducibility and reliability …

Novel approaches for imaging-based diagnosis of ocular surface disease

D Schmidl, A Schlatter, J Chua, B Tan, G Garhöfer… - Diagnostics, 2020 - mdpi.com
Imaging has become indispensable in the diagnosis and management of diseases in the
posterior part of the eye. In recent years, imaging techniques for the anterior segment are …

Human meibum and tear film derived cholesteryl and wax esters in meibomian gland dysfunction and tear film structure

S Khanal, Y Bai, W Ngo, KK Nichols, L Wilson… - The ocular …, 2022 - Elsevier
Purpose This study evaluated the presence and roles of cholesteryl esters (CEs) and wax
esters (WEs) from human tear film and meibum in meibomian gland dysfunction (MGD) …

Human precorneal tear film and lipid layer dynamics in meibomian gland dysfunction

Y Bai, W Ngo, S Khanal, KK Nichols, JJ Nichols - The ocular surface, 2021 - Elsevier
Purpose To evaluate the precorneal tear film (PCTF) and lipid layer (TFLL) thicknesses and
thinning rates in meibomian gland dysfunction (MGD) using a combined ultra-high …

[HTML][HTML] Human meibum and tear film derived (O-acyl)-omega-hydroxy fatty acids as biomarkers of tear film dynamics in meibomian gland dysfunction and dry eye …

S Khanal, Y Bai, W Ngo, KK Nichols… - … & visual science, 2021 - tvst.arvojournals.org
Purpose: To investigate the association between precorneal tear film (PCTF)–and meibum-
derived (O-Acyl)-omega-hydroxy fatty acids (OAHFAs) and PCTF thinning in meibomian …

Evaluation of systane complete for the treatment of contact lens discomfort

AD Pucker, G McGwin Jr, QX Franklin, A Nattis… - Contact Lens and …, 2020 - Elsevier
Purpose To understand if a new artificial tear, which is indicated for the treatment of both
evaporative and aqueous deficient dry eye, is able to safely alleviate contact lens discomfort …

Automatic assessment of tear film and tear meniscus parameters in healthy subjects using ultrahigh-resolution optical coherence tomography

H Stegmann, V Aranha dos Santos… - Biomedical Optics …, 2019 - opg.optica.org
Many different parameters exist for the investigation of tear film dynamics. We present a new
tear meniscus segmentation algorithm which automatically extracts tear meniscus area …

Association between dry eye parameters depends on tear components

SW Chang, WL Wu - Journal of Clinical Medicine, 2022 - mdpi.com
How tear components contribute to dry-eye symptoms/signs remains less well-defined. This
observational cross-sectional study enrolled 4817 (F/M= 3590/1227) patients. Subjective …

Silicone hydrogel versus hydrogel soft contact lenses for differences in patient‐reported eye comfort and safety

K Haworth, D Travis, L Leslie, D Fuller… - Cochrane Database …, 2023 - cochranelibrary.com
Background Ocular discomfort is the leading cause of permanent discontinuation of soft
contact lens (SCL) wear. Silicone hydrogel and hydrogel materials are the two major …

Contact lens fitting and changes in the tear film dynamics: mathematical and computational models review

D Ramasubramanian, JL Hernández-Verdejo… - Graefe's Archive for …, 2024 - Springer
Purpose This review explores mathematical models, blinking characterization, and non-
invasive techniques to enhance understanding and refine clinical interventions for ocular …