Inflammation is a biological response of the immune system that can be triggered by a
variety of factors, including pathogens, damaged cells and toxic compounds. These factors …

Depression is one of the most debilitating psychiatric disorders affecting people of all ages
worldwide. Despite significant heterogeneity between studies, increased inflammation and …

It is widely known that stimulator of interferon genes (STING) can trigger nuclear factor κB
(NF-κB) signaling. However, whether and how the NF-κB pathway affects STING signaling …

Cancer incidences are growing and cause millions of deaths worldwide. Cancer therapy is
one of the most important challenges in medicine. Improving therapeutic outcomes from …

Objective Intervertebral disc degeneration (IDD) represents major cause of low back pain.
Quercetin (QUE) is one of the approved senolytic agents. In this study, we evaluated the …

Oysters, the common name for a number of different bivalve molluscs, are the worldwide
aquaculture species and also play vital roles in the function of ecosystem. As invertebrate …

Many tumors, including breast cancer, are maintained by a subpopulation of cells that
display stem cell properties, mediate metastasis, and contribute to treatment resistance …

The high failure rate of the reductionist approach to discover effective and safe drugs to treat
chronic inflammatory diseases has led scientists to seek alternative ways. Recently …

Diabetes mellitus is one of the most common and important metabolic diseases in human.
Curcumin, which is a natural polyphenol found in turmeric, can be used in treatment of …

The pleiotropic consequences of nuclear factor of kappa light polypeptide gene enhancer in
B‐cells (NF‐κB) pathway activation result from the combinatorial effects of the five subunits …