Measles virus targets DC-SIGN to enhance dendritic cell infection

L de Witte, M Abt, S Schneider-Schaulies… - Journal of …, 2006 - Am Soc Microbiol
Dendritic cells (DCs) are involved in the pathogenesis of measles virus (MV) infection by
inducing immune suppression and possibly spreading the virus from the respiratory tract to …

[HTML][HTML] Tyrosine kinase receptor Axl enhances entry of Zaire ebolavirus without direct interactions with the viral glycoprotein

MA Brindley, CL Hunt, AS Kondratowicz, J Bowman… - Virology, 2011 - Elsevier
In a bioinformatics-based screen for cellular genes that enhance Zaire ebolavirus (ZEBOV)
transduction, AXL mRNA expression strongly correlated with ZEBOV infection. A series of …

Mannose-binding lectin binds to Ebola and Marburg envelope glycoproteins, resulting in blocking of virus interaction with DC-SIGN and complement-mediated virus …

X Ji, GG Olinger, S Aris, Y Chen… - Journal of General …, 2005 - microbiologyresearch.org
Mannose-binding lectin (MBL), a serum lectin that mediates innate immune functions
including activation of the lectin complement pathway, binds to carbohydrates expressed on …

Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences

J Misasi, K Chandran, JY Yang, B Considine… - Journal of …, 2012 - Am Soc Microbiol
Filoviruses are enveloped viruses that cause sporadic outbreaks of severe hemorrhagic
fever [CDC, MMWR Morb. Mortal. Wkly. Rep. 50: 73–77, 2001; Colebunders and Borchert, J …

Inhibition of DC-SIGN-mediated HIV infection by a linear trimannoside mimic in a tetravalent presentation

S Sattin, A Daghetti, M Thepaut, A Berzi… - ACS chemical …, 2010 - ACS Publications
HIV infection is pandemic in humans and is responsible for millions of deaths every year.
The discovery of new cellular targets that can be used to prevent the infection process …

[HTML][HTML] Raji B cells, misidentified as THP-1 cells, stimulate DC-SIGN-mediated HIV transmission

L Wu, TD Martin, M Carrington, VN KewalRamani - Virology, 2004 - Elsevier
A number of studies examining interactions of dendritic cell (DC)-specific ICAM-3 grabbing
nonintegrin (DC-SIGN) with viral pathogens have relied on monocytic transfectants as …

Camouflage and misdirection: the full-on assault of ebola virus disease

J Misasi, NJ Sullivan - Cell, 2014 - cell.com
Ebolaviruses cause a severe hemorrhagic fever syndrome that is rapidly fatal to humans
and nonhuman primates. Ebola protein interactions with host cellular proteins disrupt type I …

The role of dendritic cell C-type lectin receptors in HIV pathogenesis

S Turville, J Wilkinson, P Cameron… - Journal of Leucocyte …, 2003 - academic.oup.com
Dendritic cells play a major role in HIV pathogenesis. Epithelial dendritic cells appear to be
one of the first cells infected after sexual transmission and transfer of the virus to CD4 …

Anti-Siglec-1 antibodies block Ebola viral uptake and decrease cytoplasmic viral entry

D Perez-Zsolt, I Erkizia, M Pino, M García-Gallo… - Nature …, 2019 - nature.com
Several Ebola viruses cause outbreaks of lethal haemorrhagic fever in humans, but
developing therapies tackle only Zaire Ebola virus. Dendritic cells (DCs) are targets of this …

Baculovirus-derived human immunodeficiency virus type 1 virus-like particles activate dendritic cells and induce ex vivo T-cell responses

L Buonaguro, ML Tornesello, M Tagliamonte… - Journal of …, 2006 - Am Soc Microbiol
We have recently developed a candidate human immunodeficiency virus type 1 (HIV-1)
vaccine model based on HIV-1 Pr55 gag virus-like particles (HIV-VLPs), produced in a …