Filovirus tropism: cellular molecules for viral entry

A Takada - Frontiers in microbiology, 2012 - frontiersin.org
In human and non-human primates, filoviruses (Ebola and Marburg viruses) cause severe
hemorrhagic fever. Recently, other animals such as pigs and some species of fruit bats have …

Filoviruses: innate immunity, inflammatory cell death, and cytokines

J Lu, JM Gullett, TD Kanneganti - Pathogens, 2022 - mdpi.com
Filoviruses are a group of single-stranded negative sense RNA viruses. The most well-
known filoviruses that affect humans are ebolaviruses and marburgviruses. During infection …

Synthesis, assembly, and processing of the Env ERVWE1/syncytin human endogenous retroviral envelope

V Cheynet, A Ruggieri, G Oriol, JL Blond… - Journal of …, 2005 - Am Soc Microbiol
Syncytin is a fusogenic protein involved in the formation of the placental syncytiotrophoblast
layer. This protein is encoded by the envelope gene of the ERVWE1 proviral locus …

Glycan shield of the ebolavirus envelope glycoprotein GP

W Peng, V Rayaprolu, AD Parvate, MF Pronker… - Communications …, 2022 - nature.com
The envelope glycoprotein GP of the ebolaviruses is essential for host cell entry and the
primary target of the host antibody response. GP is heavily glycosylated with up to 17 N …

Analysis of Ebola virus entry into macrophages

F Dahlmann, N Biedenkopf, A Babler… - The Journal of …, 2015 - academic.oup.com
Ebolaviruses constitute a public health threat, particularly in Central and Western Africa.
Host cell factors required for spread of ebolaviruses may serve as targets for antiviral …

Glycosylation site-specific analysis of clade C HIV-1 envelope proteins

EP Go, Q Chang, HX Liao, LL Sutherland… - Journal of proteome …, 2009 - ACS Publications
The extensive glycosylation of HIV-1 envelope proteins (Envs), gp120/gp41, is known to
play an important role in evasion of host immune response by masking key neutralization …

Characterization of the inhibitory effect of an extract of Prunella vulgaris on Ebola virus glycoprotein (GP)-mediated virus entry and infection

X Zhang, Z Ao, A Bello, X Ran, S Liu, J Wigle… - Antiviral research, 2016 - Elsevier
Currently, no approved antiviral therapeutic is available for treatment or prevention of Ebola
virus (EBOV) infection. In this study, we characterized an EBOV-glycoprotein (GP) …

Identification of the mycobacterial carbohydrate structure that binds the C-type lectins DC-SIGN, L-SIGN and SIGNR1

EA Koppel, IS Ludwig, MS Hernandez, TL Lowary… - Immunobiology, 2004 - Elsevier
Mycobacterium tuberculosis represents a worldwide health risk and although macrophages
are primarily infected, dendritic cells (DC) are important in inducing cellular immune …

Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120

J Yolitz, C Schwing, J Chang… - Proceedings of the …, 2018 - National Acad Sciences
The HIV-1 envelope protein (Env) of early-replicating viruses encodes several distinct
transmission signatures. One such signature involves a reduced number of potential N …

[HTML][HTML] Glycosylation of minor envelope glycoproteins of porcine reproductive and respiratory syndrome virus in infectious virus recovery, receptor interaction, and …

PB Das, HLX Vu, PX Dinh, JL Cooney, B Kwon… - Virology, 2011 - Elsevier
The role of N-glycosylation of the three minor envelope glycoproteins (GP2, GP3, and GP4)
of porcine reproductive and respiratory syndrome virus (PRRSV) on infectious virus …