Synthesis and assembly of fungal melanin
HC Eisenman, A Casadevall - Applied microbiology and biotechnology, 2012 - Springer
Melanin is a unique pigment with myriad functions that is found in all biological kingdoms. It
is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) …
is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) …
The biosynthetic logic of polyketide diversity
C Hertweck - Angewandte Chemie International Edition, 2009 - Wiley Online Library
Abstract Molecular Lego: Polyketides represent a highly diverse group of natural products
with structurally intriguing carbon skeletons (see picture) which are assembled from simple …
with structurally intriguing carbon skeletons (see picture) which are assembled from simple …
Intimate bacterial–fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans
V Schroeckh, K Scherlach… - Proceedings of the …, 2009 - National Acad Sciences
Fungi produce numerous low molecular weight molecules endowed with a multitude of
biological activities. However, mining the full-genome sequences of fungi indicates that their …
biological activities. However, mining the full-genome sequences of fungi indicates that their …
Triggering cryptic natural product biosynthesis in microorganisms
K Scherlach, C Hertweck - Organic & biomolecular chemistry, 2009 - pubs.rsc.org
Natural products from microorganisms are a crucial source for novel therapeutics. Even so, it
seems that many valuable compounds are overlooked when culturing microbes under …
seems that many valuable compounds are overlooked when culturing microbes under …
Monascus secondary metabolites: production and biological activity
P Patakova - Journal of Industrial Microbiology and …, 2013 - academic.oup.com
The genus Monascus, comprising nine species, can reproduce either vegetatively with
filaments and conidia or sexually by the formation of ascospores. The most well-known …
filaments and conidia or sexually by the formation of ascospores. The most well-known …
Natural products of filamentous fungi: enzymes, genes, and their regulation
D Hoffmeister, NP Keller - Natural product reports, 2007 - pubs.rsc.org
Covering: up to June 2006We review the literature on the enzymes, genes, and whole gene
clusters underlying natural product biosyntheses and their regulation in filamentous fungi …
clusters underlying natural product biosyntheses and their regulation in filamentous fungi …
Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans
S Bergmann, J Schümann, K Scherlach… - Nature chemical …, 2007 - nature.com
In the postgenomic era it has become increasingly apparent that the vast number of
predicted biosynthesis genes of microorganisms is not reflected by the metabolic profile …
predicted biosynthesis genes of microorganisms is not reflected by the metabolic profile …
Metabolic engineering for the production of natural products
Natural products and their derivatives play an important role in modern healthcare as
frontline treatments for many diseases and as inspiration for chemically synthesized …
frontline treatments for many diseases and as inspiration for chemically synthesized …
The chemistry and biology of cytochalasans
K Scherlach, D Boettger, N Remme… - Natural product reports, 2010 - pubs.rsc.org
The chemistry and biology of cytochalasans - Natural Product Reports (RSC Publishing) DOI:10.1039/B903913A
Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article DOI: 10.1039/B903913A …
Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article DOI: 10.1039/B903913A …
Biosynthesis of polyketides by trans-AT polyketide synthases
J Piel - Natural product reports, 2010 - pubs.rsc.org
Covering: up to the end of 2008 This review discusses the biosynthesis of natural products
that are generated by trans-AT polyketide synthases, a family of catalytically versatile …
that are generated by trans-AT polyketide synthases, a family of catalytically versatile …