Signaling pathways and targeted therapy for myocardial infarction
Q Zhang, L Wang, S Wang, H Cheng, L Xu… - Signal transduction and …, 2022 - nature.com
Although the treatment of myocardial infarction (MI) has improved considerably, it is still a
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …
Macrophages play a key role in tissue repair and regeneration
Y Yu, Z Yue, M Xu, M Zhang, X Shen, Z Ma, J Li, X Xie - PeerJ, 2022 - peerj.com
Tissue regeneration after body injury has always been a complex problem to resolve for
mammals. In adult mammals, the repair process after tissue injury is often accompanied by …
mammals. In adult mammals, the repair process after tissue injury is often accompanied by …
[HTML][HTML] Anti-inflammatory effects of Allium cepa L. peel extracts via inhibition of JAK-STAT pathway in LPS-stimulated RAW264. 7 cells
HS Lee, YJ Kwon, EB Seo, SK Kim, H Lee… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Allium cepa L.(A. cepa) is one of the oldest cultivated
plants in the world. A. cepa has been used in traditional folk medicine to treat inflammatory …
plants in the world. A. cepa has been used in traditional folk medicine to treat inflammatory …
Ethyl ferulate protects against lipopolysaccharide-induced acute lung injury by activating AMPK/Nrf2 signaling pathway
Y Wu, Y Wang, Z Gao, D Chen, G Liu, B Wan… - Acta Pharmacologica …, 2021 - nature.com
Ethyl ferulate (EF) is abundant in Rhizoma Chuanxiong and grains (eg, rice and maize) and
possesses antioxidative, antiapoptotic, antirheumatic, and anti-inflammatory properties …
possesses antioxidative, antiapoptotic, antirheumatic, and anti-inflammatory properties …
Homogeneous polyporus polysaccharide inhibit bladder cancer by resetting tumor-associated macrophages toward m1 through nf-κb/nlrp3 signaling
C Liu, D He, S Zhang, H Chen, J Zhao, X Li… - Frontiers in …, 2022 - frontiersin.org
Bladder cancer (BC) is one of the most common urinary system tumors, which characterized
by a high incidence. Polyporus polysaccharide is the main active component of polyporus …
by a high incidence. Polyporus polysaccharide is the main active component of polyporus …
Neutrophil Elastase increases vascular permeability and leukocyte transmigration in cultured endothelial cells and obese mice
CJ Ushakumari, QL Zhou, YH Wang, S Na, MC Rigor… - Cells, 2022 - mdpi.com
Neutrophil elastase (NE) plays a pivotal role in inflammation. However, the mechanism
underlying NE-mediated inflammation in obesity remains unclear. Here, we report that NE …
underlying NE-mediated inflammation in obesity remains unclear. Here, we report that NE …
Senolytics cocktail dasatinib and quercetin alleviate human umbilical vein endothelial cell senescence via the TRAF6-MAPK-NF-κB axis in a YTHDF2-dependent …
T Fan, Y Du, M Zhang, AR Zhu, J Zhang - Gerontology, 2022 - karger.com
Introduction: Senescent cells play a key role in the initiation and development of various age-
related diseases. Human umbilical vein endothelial cells (HUVECs) senescence is closely …
related diseases. Human umbilical vein endothelial cells (HUVECs) senescence is closely …
RNF128 regulates neutrophil infiltration and myeloperoxidase functions to prevent acute lung injury
PY Liu, CY Chen, YL Lin, CM Lin, WC Tsai… - Cell Death & …, 2023 - nature.com
Acute lung injury (ALI) is characterised by severe pulmonary inflammation, alveolar-capillary
barrier disruption, and pulmonary oedema. Therefore, establishing effective therapeutic …
barrier disruption, and pulmonary oedema. Therefore, establishing effective therapeutic …
Particle uptake driven phagocytosis in macrophages and neutrophils enhances bacterial clearance
P Sharma, A Vijaykumar, JV Raghavan… - Journal of Controlled …, 2022 - Elsevier
Humans are exposed to numerous synthetic foreign particles in the form of drug delivery
systems and diagnostic agents. Specialized immune cells (phagocytes) clear these particles …
systems and diagnostic agents. Specialized immune cells (phagocytes) clear these particles …
Peptides regulating proliferative activity and inflammatory pathways in the monocyte/macrophage THP-1 cell line
F Avolio, S Martinotti, VK Khavinson… - International Journal of …, 2022 - mdpi.com
This study evaluates the effects of five different peptides, the Epitalon® tetrapeptide, the
Vilon® dipeptide, the Thymogen® dipeptide, the Thymalin® peptide complex, and the …
Vilon® dipeptide, the Thymogen® dipeptide, the Thymalin® peptide complex, and the …