Colchicine is an ancient herbal drug derived from Colchicum autumnale. It was first used to
treat familial Mediterranean fever and gout. Based on its unique efficacy as an anti …

Carcinogenesis is a multistep process triggered by genetic alterations that activate different
signal transduction pathways and cause the progressive transformation of a normal cell into …

Bark protects the tree against environmental insults. Here, we analyzed whether this
defensive strategy could be utilized to broadly enhance protection against colitis. As a proof …

Transdifferentiation of epithelial cells into cells with mesenchymal properties and
appearance, that is, epithelial–mesenchymal transition (EMT), is essential during …

In recent years several drugs have been developed deriving from traditional products and
current drug research is actively investigating the possible therapeutic roles of many …

TGF‐β signaling pathway plays a key role in breast cancer metastasis. Recent studies
suggest that TGF‐β regulates tumor progression and invasion not only via transcriptional …

Review covering up to 07/2019 (−)-Parthenolide is a germacrane sesquiterpene lactone,
available in ample amounts from the traditional medical plant feverfew (Tanacetum …

Despite rapid advances in many fronts, pancreatic cancer (PC) remains one of the most
difficult human malignancies to treat due, in part, to de novo and acquired chemoresistance …

Background Spermidine, a naturally occurring polyamine, displays a wide variety of internal
biological activities including cell growth and proliferation. However, the molecular …

As far as health benefit is concerned, dark tea is one of the best beverages in the world.
Theabrownins are the major ingredient contributing to the health benefits of dark tea and …