Hypervalent aryliodoumiums are intensively investigated as arylating agents. They are
excellent surrogates to aryl halides, and moreover they exhibit better reactivity, which allows …

Coumarins are naturally occurring molecules with a versatile range of activities. Their
structural and physicochemical characteristics make them a privileged scaffold in medicinal …

Cancer is one of the leading causes of death globally, around 10 million deaths are reported
every year due to cancer. Some clinically approved anticancer drugs play a riveting role in …

Pyrazole derivatives, as a class of heterocyclic compounds, possess unique chemical
structures that confer them with a broad spectrum of pharmacological activities. They have …

Pyrazolines are a significant class of heterocyclic compounds with essential biological
activities. They are quite stable, which has inspired medicinal chemists to experiment with …

Cancer is a serious threat to human beings and is the second-largest cause of death all over
the globe. Chemotherapy is one of the most common treatments for cancer; however, drug …

In the present work, a concise library of 1, 3, 5-triaryl-2-pyrazolines (2a–2q) was designed
and synthesized by employing a multistep strategy, and the newly synthesized compounds …

Aldose reductase (AR) acts as a multi-disease target for the design and development of
therapeutic agents for the management of diabetic complications as well as non-diabetic …

In this work, analog 3b (5-(4-(dimethylamino) phenyl)-3-(4-methoxyphenyl)-4, 5-dihydro-1H-
pyrazole-1-carbothioamide) of pyrazoline derivative was produced based on the active site …

The palladium‐catalyzed asymmetric carboamination reaction is one of the most significant
transformations in organic chemistry. Herein, we report the first palladium‐catalyzed …