The use of non-standard toxicity models is a hurdle in the early development of antimicrobial
peptides towards clinical applications. Herein we report an extensive in vitro and in vivo …

In the search for new sources of antimicrobials many researchers have investigated
antimicrobial peptides (AMPs) as templates for the design of innovative therapeutics …

The increasing rate of antibiotic resistance constitutes a global health crisis. Antimicrobial
peptides (AMPs) have the property to selectively kill bacteria regardless of resistance to …

In recent decades, bioactive peptides have been gaining recognition in various biomedical
areas, such as intracellular drug delivery (cell-penetrating peptides, CPPs) or anti-infective …

The poor stability of antibacterial peptide to protease limits its clinical application. Among
these limitations, trypsin mainly exists in digestive tract, which is an insurmountable obstacle …

Supramolecular antimicrobial hydrogels based on peptides are attractive soft materials for
the treatment of infections, considering their ease of preparation and benign fate in …

Microbial resistance to available drugs is a growing health threat imposing the need for the
development of new drugs. The scaffold of plant defensins, including their γ-cores, are …

The increasing emergence of multi-drug resistant bacteria is a serious threat to public health
worldwide. Antimicrobial peptides have attracted attention as potential antibiotics since they …

Peptoids are a class of peptidomimetics in which the side chain is bound to the backbone
nitrogen rather than the α-carbon, giving N-substituted glycine oligomers. Compared to …

Monodisperse, sequence‐specific oligomers that adopt regular three‐dimensional
structures, termed foldamers, have found widespread use as biomimetics, sensors, and …