[HTML][HTML] Liposome-integrated hydrogel hybrids: Promising platforms for cancer therapy and tissue regeneration

M Sanati, SA Yavari - Journal of Controlled Release, 2024 - Elsevier
Drug delivery platforms have gracefully emerged as an indispensable component of novel
cancer chemotherapy, bestowing targeted drug distribution, elevating therapeutic effects …

Hierarchical composite scaffold with deferoxamine delivery system to promote bone regeneration via optimizing angiogenesis

R Wang, X Zha, J Chen, R Fu, Y Fu… - Advanced …, 2024 - Wiley Online Library
A bone defect refers to the loss of bone tissue caused by trauma or lesions. Bone defects
result in high morbidity and deformity rates worldwide. Autologous bone grafting has been …

Application of Deferoxamine in Tissue Regeneration Attributed to Promoted Angiogenesis

H Shen, Y Ma, Y Qiao, C Zhang, J Chen, R Zhang - Molecules, 2024 - mdpi.com
Deferoxamine, an iron chelator used to treat diseases caused by excess iron, has had a
Food and Drug Administration-approved status for many years. A large number of studies …

Deferoxamine functionalized alginate-based collagen composite material enhances the integration of metal implant and bone interface

Z Che, X Sheng, Q Sun, Y Wu, K Song, A Chen… - Carbohydrate …, 2024 - Elsevier
Poor osseointegration markedly compromises the longevity of prostheses. To enhance the
stability of titanium implants, surface functionalization is a proven strategy to promote …

Diradicaloid-Loaded Polypeptide Nanoparticles for Two-Photon NIR Phototheranostics

D Chen, Y Xu, Y Wang, X Li, D Yin… - ACS Applied Materials & …, 2024 - ACS Publications
Stable organic radicals, with unique electronic transitions from the ground state (D0) to the
doublet excited state (D1), show promise as high-fluorescence quantum yield dyes. While …

Deferoxamine protects cochlear hair cells and hair cell-like HEI-OC1 cells against tert-butyl hydroperoxide-induced ototoxicity

PH Lu, PW Ma, WL Wang, W Gao, JW Chen… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Oxidative stress is the common mechanism of sensorineural hearing loss (SNHL) caused by
many factors, such as noise, drugs and ageing. Here, we used tert-butyl hydroperoxide (t …

α-ketoglutarate preconditioning extends the survival of engrafted adipose-derived mesenchymal stem cells to accelerate healing of burn wounds

S Li, C Zhao, G Shang, J Xie, L Cui, Q Zhang… - Experimental Cell …, 2024 - Elsevier
The application of adipose-derived stem cells (ADSCs) in treating hard-to-heal wounds has
been widely accepted, while the short-term survival rate remains an obstacle in stem cell …

Preconditioning of human umbilical cord mesenchymal stem cells with deferoxamine potentiates the capacity of the secretome released from the cells and promotes …

B Isildar, S Ozkan, H Sahin, M Ercin… - International …, 2024 - Elsevier
This study aimed to examine the effects of the secretome released by human umbilical cord-
mesenchymal stem cells (MSC) as a result of preconditioning with deferoxamine (DFX), a …

Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

J Ung, SF Tan, TE Fox, JJP Shaw, M Taori, BJ Horton… - Cancers, 2023 - mdpi.com
Simple Summary The lysosomal lipid hydrolase acid ceramidase is upregulated in acute
myeloid leukemia and promotes leukemic blast survival, underscoring its potential for …

Identification of TNFRSF1A as a potential biomarker for osteosarcoma

Y Zhang, K Liu, J Wang - Cancer Biomarkers, 2024 - content.iospress.com
BACKGROUND: Osteosarcoma (OS) is a relatively rare malignant bone tumor in teenagers;
however, its molecular mechanisms are not yet understood comprehensively. OBJECTIVE …