[HTML][HTML] Monoclonal antibody anti-PBP2a protects mice against MRSA (methicillin-resistant Staphylococcus aureus) infections

FB Saraiva, ACC de Araújo, AÉV de Araújo… - PLoS …, 2019 - journals.plos.org
Methicillin-resistant Staphylococcus aureus (MRSA) is a multidrug-resistant bacterium
responsible for serious nosocomial and community-acquired infections worldwide. Since …

[引用][C] 金黄色葡萄球菌表面蛋白研究进展

周宏, 李韩平, 姜永强, 熊正英 - 生物技术通讯, 2004

Passive immunization against methicillin resistant Staphylococcus aureus recombinant PBP2a in sepsis model of mice: comparable results with antibiotic therapy

RZ Naghshbandi, S Haghighat, M Mahdavi - International …, 2018 - Elsevier
Methicillin resistant Staphylococcus aureus (MRSA) is a representative pathogen that is
responsible for a nosocomial infection and considerable yearly mortality rate. Antibiotic …

Recombinant PBP2a of methicillin-resistant S. aureus formulation in Alum and Montanide ISA266 adjuvants induced cellular and humoral immune responses with …

SS Mortazavi, S Haghighat, M Mahdavi - Microbial pathogenesis, 2020 - Elsevier
Staphylococcus aureus is an important cause of both hospital and community acquired
infections worldwide. S. aureus can develop multidrug resistance; thus, immunotherapy can …

Treatment and prevention of enterococcal infections–alternative and experimental approaches

S Koch, M Hufnagel, J Huebner - Expert opinion on biological …, 2004 - Taylor & Francis
Enterococci are one of the leading types of organisms isolated from infections of
hospitalised patients and the third most common cause of nosocomial bloodstream …

[PDF][PDF] 176 例新生儿败血症临床分析

朱绪亮, 杨嘉琛, 吴星恒, 赵玲, 陈晓 - 中国当代儿科杂志, 2009 - zgddek.com
&& 新生儿败血症是新生儿期较严重的感染性疾病, 在我国其发病率及病死率仍较高.
本文通过回顾分析南昌大学第一附属医院# $$# 年G 月至# $$" 年Y 月! GY …

Recombinant PBP2a as a vaccine candidate against methicillin-resistant Staphylococcus aureus: Immunogenicity and protectivity

S Haghighat, SD Siadat, SMR Sorkhabadi… - Microbial …, 2017 - Elsevier
Methicillin-resistant Staphylococcus aureus infections are focal and development of an
effective vaccine can help to control this infection. Here, recombinant PBP2a was studied in …

[引用][C] 预测蛋白质间相互作用的生物信息学方法

朱新宇, 沈百荣 - 生物技术通讯, 2004

[HTML][HTML] Prediction of Burkholderia pseudomallei DsbA substrates identifies potential virulence factors and vaccine targets

B Vezina, GA Petit, JL Martin, MA Halili - PLoS One, 2020 - journals.plos.org
Identification of bacterial virulence factors is critical for understanding disease pathogenesis,
drug discovery and vaccine development. In this study we used two approaches to predict …

Lack of protection of mice against Staphylococcus aureus despite a significant immune response to immunization with a DNA vaccine encoding collagen-binding …

R Therrien, P Lacasse, G Grondin, BG Talbot - Vaccine, 2007 - Elsevier
Collagen-binding protein (CNA) is the major Staphylococcus aureus adhesin responsible for
high affinity binding to collagen and is assumed to be a major virulence factor in infection …