Mastitis is considered the costliest disease on dairy farms and also adversely affects animal
welfare. As treatment (and to a lesser extent prevention) of mastitis rely heavily on …

Antibiotic resistance poses a growing threat to global public health. It is urgent to develop
new alternative antibiotics. Antimicrobial peptide (AMP) is a diverse class of natural …

Antimicrobial resistance is a leading cause of mortality, calling for the development of new
antibiotics. The fungal antibiotic plectasin is a eukaryotic host defence peptide that blocks …

Although antimicrobial peptides (AMPs) have highly desirable intrinsic characteristics in
their commercial product development as new antimicrobials, the limitations of AMPs from …

The long-term use of antibiotics has accelerated the emergence of antibiotic-resistant
bacteria (ARB). Annual global death due to antibiotic resistance is over 700,000 in 2014, it is …

ABSTRACT A marine arenicin-3 derivative, N4, displayed potent antibacterial activity
against Gram-negative bacteria, but its antibacterial mode of action remains elusive. The …

Abstract Treatment of Staphylococcus aureus infections remains very difficult due to its
capacity to survive intracellularly and its multidrug resistance. In this study, the extracellular …

(1) Background: Based on the hazard of Streptococcus agalactiae to human and animal
health and the increasing drug resistance, it is urgent to develop new antimicrobial agents …

Non-computational classical evolution analysis of plectasin and its functional relatives can
especially contribute tool value during access to meet requirements for their better …

Insect defensins are promising candidates for the development of potent antimicrobials
against antibiotic-resistant Staphylococcus aureus (S. aureus). An insect defensin, DLP4 …