BACKGROUND Numerous studies have reported declines in semen quality and other
markers of male reproductive health. Our previous meta-analysis reported a significant …

A severe decline in child births has occurred over the past half century, which will lead to
considerable population declines, particularly in industrialized regions. A crucial question is …

Abstract Paracetamol (N-acetyl-p-aminophenol (APAP), otherwise known as
acetaminophen) is the active ingredient in more than 600 medications used to relieve mild to …

Endocrine disrupting chemicals (EDCs) are ubiquitous in aquatic and terrestrial
environments. The main objective of this review was to summarize the current knowledge of …

Clinical infertility is the inability of a couple to conceive after 12 months of trying. Male factors
are estimated to contribute to 30–50% of cases of infertility. Infertility or reduced fertility can …

BACKGROUND Reported declines in sperm counts remain controversial today and recent
trends are unknown. A definitive meta-analysis is critical given the predictive value of sperm …

A diverse array of sex determination (SD) mechanisms, encompassing environmental to
genetic, have been found to exist among vertebrates, covering a spectrum from fixed SD …

Male infertility is an attracting growing concern owing to decline in sperm quality of men
worldwide. Phthalates, in particular to di (2-ethylhexyl) phthalate (DEHP) or its main …

Germ-cell tumours (GCTs) affect predominantly younger males aged between 15 and 40
years, with nearly 74 500 new cases estimated globally in 2020. 1 About one-third of all GCT …

BACKGROUND Herein, we describe the consensus guideline methodology, summarize the
evidence-based recommendations we provided to the World Health Organization (WHO) for …