This monograph, written by the pioneers of IVF and reproductive medicine, celebrates the
history, achievements, and medical advancements made over the last 40 years in this …

Context Male infertility is defined as the inability to conceive following 1 year of regular
unprotected intercourse. It is the causative factor in 50% of couples and a leading indication …

Over the past century, evidence has emerged that endocrine disrupting chemicals (EDCs)
have an impact on reproductive health. An increased frequency of reproductive disorders …

There is an emerging body of evidence suggesting that male infertility may be a harbinger of
future health. Potential associations between infertility and health may arise from genetic …

Background P-element–induced wimpy testis (PIWI)–interacting RNAs (piRNAs) are short
(21 to 35 nucleotides in length) and noncoding and are found almost exclusively in germ …

Background: Diabetes reduces semen quality and increasingly occurs during reproductive
years. Diabetes medications, such as metformin, have glucose-independent effects on the …

The chemical pollution crisis severely threatens human and environmental health globally.
To tackle this challenge the establishment of an overarching international science–policy …

Objective High-fat diet (HFD)-induced metabolic disorders can lead to impaired sperm
production. We aim to investigate if HFD-induced gut microbiota dysbiosis can functionally …

Infertility is a growing global health issue with far-reaching socioeconomic implications. A
downward trend in male fertility highlights the acute need for affordable and accessible …

The complex morphology of the Sertoli cells and their interactions with germ cells has been
a focus of investigators since they were first described by Enrico Sertoli. In the past 50 years …