Infertility is a growing global health issue with far-reaching socioeconomic implications. A
downward trend in male fertility highlights the acute need for affordable and accessible …

The complex morphology of the Sertoli cells and their interactions with germ cells has been
a focus of investigators since they were first described by Enrico Sertoli. In the past 50 years …

Male reproductive development is intricately dependent on fetal androgen action.
Consequently, disrupted androgen action during fetal life can interfere with the development …

Although semen quality is an important determinant of fertility, defining clear thresholds for
normal ranges has proven difficult. According to'time to pregnancy'studies, fecundity starts to …

Background Semen quality in men continues to decline in Western countries, but the
contours of the issue remain obscure, in relation to contributing chemicals. Objectives To …

A marked reduction in fertility and an increase in adverse reproductive outcomes during the
last few decades have been associated with occupational and environmental chemical …

Background Semen quality, a predictor of male fertility, has been suggested declining
worldwide. Among other life style factors, male coffee/caffeine consumption was …

Abstract Di-(2-ethylhexyl) phthalate (DEHP) is a common environmental endocrine
disrupting chemical that may induce male reproductive disorders. Exposure to DEHP at a …

Testicular germ cell tumours (TGCTs) are the most frequent cancer type in young men and
originate from the common precursor germ cell neoplasia in situ (GCNIS). For decades …

Over the past four decades, studies of various designs have reported spatial and temporal
trends in human semen quality. Several standardized-methodology studies in …