Per-and poly-fluoroalkyl substances (PFASs) have been widely used and detected in human
matrices. Evidence that PFAS exposure may be associated with adverse human …

Indiscriminate use of synthetic chemical compounds and the unregulated presence of heavy
metals threatens the integral reproducibility of mankind and other living organisms. The …

Background Previous studies have demonstrated widespread exposure of humans to
certain benzophenones commonly used as UV filters or UV absorbers; some of which have …

Currently, most men with infertility cannot be given an aetiology, which reflects a lack of
knowledge around gamete production and how it is affected by genetics and the …

Sperm counts have shown a progressive decline across the world since the mid‐1900s.
Global rates of obesity have been climbing at a similarly alarming rate, suggesting that these …

Non-obstructive azoospermia (NOA) is a serious cause of male infertility. The Sertoli cell
responds to androgens and takes on roles supporting spermatogenesis, which may cause …

Infertility affects nearly 186 million people worldwide and the male partner is the cause in
about half of the cases. Meta-regression data indicate an unexplained decline in sperm …

Abstract Purpose Endocrine disruptors (EDs) are exogenous substances able to impair
endocrine system; consequently, they may cause numerous adverse effects. Over the last …

The incidence of many hormone-dependent diseases, including testicular cancer, has
sharply increased in all high-income countries during the 20th century. This is not fully …

Male infertility is a global reproductive issue, several clinical approaches have been
developed to tackle it, but their effectiveness is limited by the labour-intensive and time …