[HTML][HTML] Mutual regulation of TGFβ-induced oncogenic EMT, cell cycle progression and the DDR

H Schuhwerk, T Brabletz - Seminars in Cancer Biology, 2023 - Elsevier
TGFβ signaling and the DNA damage response (DDR) are two cellular toolboxes with a
strong impact on cancer biology. While TGFβ as a pleiotropic cytokine affects essentially all …

The caspase-activated DNase promotes cellular senescence

A Haimovici, V Rupp, T Amer, A Moeed, A Weber… - The EMBO …, 2024 - embopress.org
Cellular senescence is a response to many stressful insults. DNA damage is a consistent
feature of senescent cells, but in many cases its source remains unknown. Here, we identify …

[HTML][HTML] Transient caspase-mediated activation of caspase-activated DNase causes DNA damage required for phagocytic macrophage differentiation

D Maurya, G Rai, D Mandal, BC Mondal - Cell Reports, 2024 - cell.com
Phagocytic macrophages are crucial for innate immunity and tissue homeostasis. Most
tissue-resident macrophages develop from embryonic precursors that populate every organ …

Macrophage differentiation requires DNA damage caused by Caspase-Activated DNase

D Maurya, G Rai, D Mandal, BC Mondal - bioRxiv, 2023 - biorxiv.org
Phagocytic macrophages are crucial for innate immunity and tissue homeostasis. Most
macrophages develop from embryonic precursors that populate every organ before birth to …

[PDF][PDF] Sensory Consciousness and the Acquisition of Perceptional Reality. How We Know That We Know

IP Janecka - American Journal of Educational Research, 2023 - researchgate.net
The past, present and likely all future societies will have continued to engage in ongoing
mutual conflicts, resembling stormy waves, on all levels and scales. Human genetics or …