Improving trends in global health care have resulted in a steady increase in the geriatric
population. However, as the population ages, surgery is being performed more frequently in …

Approximately 12% of apparently previously cognitively well patients undergoing
anaesthesia and noncardiac surgery will develop symptoms of cognitive dysfunction after …

Postoperative cognitive dysfunction (POCD) is defined by cognitive impairment determined
by neuropsychological tests from before to after surgery. Several mechanisms have been …

Postoperative delirium and cognitive dysfunction (POCD) are topics of special importance in
the geriatric surgical population. They are separate entities, whose relationship has yet to be …

Post-operative cognitive complications such as delirium have been consistently associated
with poor short and long term outcomes, and the role of anesthesia, particularly the role of …

There is evidence that postoperative cognitive dysfunction (POCD) is a significant problem
after major surgery, but the pathophysiology has not been fully elucidated. The interpretation …

The authors performed a meta-analysis and found that epidural analgesia overall provided
superior postoperative analgesia compared with intravenous patient-controlled analgesia …

Background Postoperative cognitive dysfunction is being increasingly reported as a
complication. The authors investigated the role of cytokine-mediated inflammation within the …

IMPLICATIONS: The current systematic review demonstrates that there are only a few
clinical trials that compare opioid analgesics or analgesic modalities. Meperidine appears to …

Surgery and anaesthesia exert comparatively greater adverse effects on the elderly than on
the younger brain, manifest by the higher prevalence of postoperative delirium and cognitive …