Departments of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical
School, Tokyo, Japan Colorectal cancer (CRC) is the third most common cancer worldwide …

Suitable lesions for endoscopic treatment include not only early colorectal carcinomas but
also several types of precarcinomatous adenomas. It is important to establish practical …

Importance For patients withRASwild-type metastatic colorectal cancer, adding anti–
epidermal growth factor receptor (anti-EGFR) or anti–vascular endothelial growth factor (anti …

Background Accurate clinical staging is crucial to managing gastrointestinal cancer, but
fluorine 18 (18F) fluorodeoxyglucose (FDG) PET/CT has limitations. Targeting fibroblast …

The prognostication of colorectal cancer (CRC) has traditionally relied on staging as defined
by the Union for International Cancer Control (UICC) and American Joint Committee on …

Background & Aims In accordance with guidelines, most patients with T1 colorectal cancers
(CRC) undergo surgical resection with lymph node dissection, despite the low incidence (∼ …

Background & Aims Deep submucosal invasion (DSI) is considered a key risk factor for
lymph node metastasis (LNM) and important criterion to recommend surgery in T1 colorectal …

Hereditary colorectal cancer (HCRC) accounts for< 5% of all colorectal cancer cases. Some
of the unique characteristics commonly encountered in HCRC cases include early age of …

(1) Background: Colorectal cancer (CRC) is the third most common cancer and the second
leading cause of cancer-related mortality worldwide. Up to 50% of patients with CRC …

Purpose The role of tumor-infiltrating lymphocytes (TILs) in predicting lymph node
metastasis (LNM) in patients with T1 colorectal cancer (CRC) remains unclear. Furthermore …