Lung cancer is the deadliest malignancy worldwide. An inflammatory microenvironment is a
key factor contributing to lung tumor progression. Tumor-Associated Macrophages (TAMs) …

The extracellular matrix (ECM) is a critical cue to direct tumorigenesis and metastasis.
Although two-dimensional (2D) culture models have been widely employed to understand …

With the development in tumor immunology, people are gradually understanding the
complexity and diversity of the tumor microenvironment immune status and its important …

Inflammatory cells and mediators form a major part of the tumor microenvironment and play
important roles in the regulation of cancer initiation, tumor cell proliferation, and metastasis …

ALK-positive NSCLC patients demonstrate initial responses to ALK tyrosine kinase inhibitor
(TKI) treatments, but eventually develop resistance, causing rapid tumor relapse and poor …

Inflammation plays a significant role in carcinogenesis and tumor growth. The current study
was designed to test the hypothesis that resolvin E1 (RvE1) and overexpression of the …

Metastasis is a multi-step process in which direct crosstalk between cancer cells and their
microenvironment plays a key role. Here, we assessed the effect of paired tumor-associated …

Alterations in circulating Cu and Zn are negative predictors of survival in neoplastic patients
and are known during lung cancer. However, no data on predicting mortality of lung cancer …

Lung cancer is the most common and most fatal of all malignancies worldwide. Furthermore,
with more than half of all lung cancer patients presenting with distant metastases at the time …

Disrupted alternative polyadenylation (APA) is frequently involved in tumorigenesis and
cancer progression by regulating the gene expression of oncogenes and tumor …