Hexokinase 2 discerns a novel circulating tumor cell population associated with poor prognosis in lung cancer patients

L Yang, X Yan, J Chen, Q Zhan… - Proceedings of the …, 2021 - National Acad Sciences
Unlike other epithelial cancer types, circulating tumor cells (CTCs) are less frequently
detected in the peripheral blood of non–small cell lung cancer (NSCLC) patients using …

[HTML][HTML] Intercellular communication in malignant pleural mesothelioma: properties of tunneling nanotubes

JW Ady, S Desir, V Thayanithy, RI Vogel… - Frontiers in …, 2014 - frontiersin.org
Malignant pleural mesothelioma is a particularly aggressive and locally invasive malignancy
with a poor prognosis despite advances in understanding of cancer cell biology and …

[HTML][HTML] Clinicopathological and prognostic significance of Oct-4 expression in patients with non-small cell lung cancer: a systematic review and meta-analysis

SJ Li, J Huang, XD Zhou, WB Zhang… - Journal of thoracic …, 2016 - ncbi.nlm.nih.gov
Background Octamer-binding transcription factor 4 (Oct-4) has been identified to participate
in the tumorigenicity and malignancy of non-small cell lung cancer (NSCLC). However, its …

[HTML][HTML] EGFR mutation status in lung adenocarcinoma-associated malignant pleural effusion and efficacy of EGFR tyrosine kinase inhibitors

J Yang, OJ Lee, SM Son, CG Woo… - … : official journal of …, 2018 - synapse.koreamed.org
Purpose Malignant pleural effusions (MPEs) are often observed in lung cancer, particularly
adenocarcinoma. The aim of this study was to investigate epidermal growth factor receptor …

Cell dynamics in malignant pleural effusions

E Giarnieri, G Bellipanni, M Macaluso… - Journal of Cellular …, 2015 - Wiley Online Library
Malignant pleural effusions (MPEs) are a common manifestation found in patients with lung
cancer. After cytological and histological confirmation of malignancy, talc pleurodesis still …

[HTML][HTML] The prognostic value of whole blood, and mRNA expression in advanced small-cell lung cancer

E Sodja, M Rijavec, A Koren, A Sadikov… - Radiology and …, 2016 - sciendo.com
Background. The data on expression and clinical impact of cancer stem cell markers SOX2,
NANOG and OCT4 in lung cancer is still lacking. The aim of our study was to compare …

[HTML][HTML] Incorporating radiomic feature of pretreatment 18F-FDG PET improves survival stratification in patients with EGFR-mutated lung adenocarcinoma

YH Chen, TF Wang, SC Chu, CB Lin, LY Wang… - PLoS …, 2020 - journals.plos.org
Background To investigate the survival prognostic value of the radiomic features of 18F-FDG
PET in patients who had EGFR (epidermal growth factor receptor) mutated lung …

Cell migration microfluidics for electrotaxis-based heterogeneity study of lung cancer cells

Y Li, T Xu, H Zou, X Chen, D Sun, M Yang - Biosensors and Bioelectronics, 2017 - Elsevier
Tumor metastasis involves the migration of cells from primary site to a distant location.
Recently, it was established that cancer cells from the same tumor were heterogeneous in …

Active targeting docetaxel-PLA nanoparticles eradicate circulating lung cancer stem-like cells and inhibit liver metastasis

N Yang, Y Jiang, H Zhang, B Sun, C Hou… - Molecular …, 2015 - ACS Publications
Lung cancer is the major cause of cancer related lethality worldwide, and metastasis to
distant organs is the pivotal cause of death for the vast majority of lung cancer patients …

[HTML][HTML] Malignant pleural effusion and ascites induce epithelial-mesenchymal transition and cancer stem-like cell properties via the vascular endothelial growth factor …

T Yin, G Wang, S He, G Shen, C Su, Y Zhang… - Journal of Biological …, 2016 - ASBMB
Malignant pleural effusion (PE) and ascites, common clinical manifestations in advanced
cancer patients, are associated with a poor prognosis. However, the biological …