Hepatitis B virus (HBV) is a major pathogen that causes acute/chronic hepatitis. Continuous
HBV infection can lead to the development of hepatocellular carcinoma (HCC). Although …

A period of about a decade has been estimated to pass for the emergence of a new
infectious strain of a virus that may lead to the occurrence of a pandemic one. It is now …

Glycosynthases are mutant glycosyl hydrolases that can synthesize glycosidic bonds
between acceptor glycone/aglycone groups and activated donor sugars with suitable …

Glycosylation in host cells and viruses is an important factor in viral infection and a target for
anti-viral therapy. Hepatitis B virus (HBV) is a major pathogen causing acute/chronic …

Biopharmaceutical drug modalities derived from animal cell culture are inherently complex
and heterogeneous by nature. Among the most complex of these biologic entities are …

Objectives Gene therapy based on recombinant adeno‐associated viral (rAAV) vectors has
been proved to be clinically effective for genetic diseases. However, there are still some …

Antiretroviral therapy (ART) is the first treatment for HIV/AIDS cases, it is known to improve
the patient's quality of life, but cannot cure HIV infection. HIV is a virus that infects CD4+, this …

Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …

High-parameter single-cell phenotyping has enabled in-depth classification and
interrogation of immune cells, but to date has not allowed for glycan characterization. Here …

Abstract Syndrome Acute Respiratory Syndrome Corona Virus-2 (SARS COV2) is the virus
that causes the COVID19 disease and has caused more than 4 million deaths worldwide …