Generation and characterization of a novel candidate gene therapy and vaccination vector based on human species D adenovirus type 56

MR Duffy, J Alonso-Padilla, L John… - Journal of General …, 2018 - microbiologyresearch.org
The vectorization of rare human adenovirus (HAdV) types will widen our knowledge of this
family and their interaction with cells, tissues and organs. In this study we focus on HAdV-56 …

[HTML][HTML] Human Ad19a/64 HERV-W Vaccines Uncover Immunosuppression Domain-Dependent T-Cell Response Differences in Inbred Mice

I Skandorff, E Ragonnaud, J Gille… - International Journal of …, 2023 - mdpi.com
Expression of human endogenous retrovirus type W (HERV-W) has been linked to cancer,
making HERV-W antigens potential targets for therapeutic cancer vaccines. In a previous …

[HTML][HTML] Species D adenoviruses as oncolytic viral vectors

BL Bullard, BN Corder, EA Weaver - Viruses, 2020 - mdpi.com
Oncolytic adenoviruses (Ad) have shown promising results in the therapeutic treatment of
cancer. Ad type 5 (Ad5) is the most extensively utilized Ad type. However, several limitations …

[PDF][PDF] 全骨髓贴壁并差速传代分离纯化大鼠骨髓间充质干细胞: 与密度梯度离心法的比较

林楚伟, 周胜华, 杜优优 - 中国组织工程研究与临床康复, 2010 - cjter.com
全骨髓贴壁并差速传代分离纯化大鼠骨髓间充质干细胞: 与密度梯度离心法的比较*☆ Page 1 中国
组织工程研究与临床康复第14 卷第14 期2010–04–02 出版 Journal of Clinical Rehabilitative …

大鼠骨髓间充质干细胞的分离培养及鉴定

杨晋, 李映红, 张永锋, 张莉, 胡银清 - 深圳中西医结合杂志, 2008 - cqvip.com
目的: 探索体外分离培养及纯化SD 大鼠骨髓间充质干细胞(mesenchymal stromal cells, MSCs)
的方法. 方法: 采用贴壁分离和消化控制相结合的方法, 分离纯化3~ 4 周龄大鼠MSCs …

Gene therapy for hypertension

L Paulis, H Franke, F Simko - Expert Opinion on Biological Therapy, 2017 - Taylor & Francis
Introduction: The control of hypertension and the resulting cardiovascular events is still
insufficient. Thus, the search for novel means for blood pressure (BP) reduction remains …

骨髓间充质干细胞分离培养及在移植肝中定居能力的研究

朱金海, 陈燕凌 - 福建医科大学学报, 2010 - cqvip.com
目的体外分离培养并鉴定扩增大鼠骨髓间充质干细胞(MSC), 观察MSC 在肝移植受体内的定居
能力. 方法直接贴壁法培养大鼠MSC, 绘制细胞生长曲线; 流式细胞仪检测细胞表面标志 …

[HTML][HTML] Vaccine vectors based on Adenovirus 19a/64 exhibit broad cellular tropism and potently restimulate HCMV-specific T cell responses ex vivo

R Kiener, M Fleischmann, C Schwegler, Z Ruzsics… - Scientific Reports, 2018 - nature.com
Human Cytomegalovirus (HCMV) remains a major health burden and the development of a
vaccine is a global priority. We developed new viral vectors delivering the T cell …

骨髓间充质干细胞成骨方向诱导过程中的基因表达

胡杨, 马莹, 何惠宇, 盛磊 - 中国组织工程研究, 2010 - cjter.com
背景: 目前骨髓间充质干细胞向成骨细胞分化演变中的基因表达模式尚不明确. 目的:
观察骨髓间充质干细胞向成骨细胞诱导分化过程中碱性磷酸酶, 骨桥蛋白, Ⅰ 型胶原 …

Gene silencing of myofibrillogenesis regulator-1 by adenovirus-delivered small interfering RNA suppresses cardiac hypertrophy induced by angiotensin II in mice

W Dai, W He, G Shang, J Jiang… - American Journal of …, 2010 - journals.physiology.org
Our previous studies proved that myofibrillogenesis regulator (MR)-1 has a close
relationship with cardiac hypertrophy induced by ANG II. In the present study, we developed …