Three-dimensional (3D) printing has gained popularity in tissue engineering and in the field
of cartilage regeneration. This is due to its potential to generate scaffolds with spatial …

Despite huge efforts, tissue engineers and orthopedic surgeons still face a great challenge
to functionally repair osteochondral (OC) defects. Nevertheless, over the past decade great …

Photo-crosslinked chitosan-gelatin scaffolds were fabricated and applied for chondrocyte
culture in vitro. Photocurable methacryloyl chitosan was synthesized and characterized by …

A general problem in tissue engineering is the poor and insufficient blood supply to
guarantee tissue cell survival as well as physiological tissue function. To address this …

Background Due to very sluggish turnover at the molecular and cellular level, the healing of
chondral damages has been considered difficult. In the current study, the effects of the …

Background Cartilage repair is a challenging research area because of the limited healing
capacity of adult articular cartilage. We had previously developed a natural, human cartilage …

Lately, cellular-based cartilage joint therapies have gradually gained more attention, which
leads to next generation bioengineering approaches in the development of cell-based …

ABSTRACT AIM: In case of refractory knee osteoarthritis at a relatively young age causing
persisting pain, treatment options are limited. In case of medial degeneration high tibial …

Hard tissues including teeth, bone and cartilage have inability or poor capacity to self-renew,
especially in large defects. Therefore, repair of damages in these tissues represents a huge …

Aim: To evaluate the utility of a novel nanocomposite biomaterial consisting of poly-L/D-
lactide, and hydroxyapatite bioceramics, enriched with sodium alginate in articular cartilage …