Pain is frequently reported during cancer disease, and it still remains poorly controlled in
40% of patients. Recent developments in oncology have helped to better control pain …

Purines and purinergic receptors are widely distributed throughout the human body. Purine
molecules within cells play crucial roles in regulating energy metabolism and other cellular …

Since pain is common in many diseases, it is important to summarize the precise prevalence
data on pain and high-impact pain, which frequently worsens the quality of life and work …

Pain is one of the most prevalent and difficult to manage symptoms in cancer patients, and
conventional drugs present a range of adverse reactions. The development of β …

Perineural invasion (PNI) is the process through which tumors invade and interact with
nerves. The dynamic changes in the nerves caused by PNI may induce disturbing …

Background Opioid dose titration is a fundamental process of opioid therapy in cancer pain.
Aims To assess data opioid dose titration. Methods The principal opioid dose titration …

Breast cancer is a global health concern, with increasing disease burden and disparities in
access to healthcare. Late diagnosis and limited treatment options in underserved areas …

Cancer-related fatigue (CRF) is one of the most prevalent and detrimental complications of
cancer. Emerging evidence suggests that obesity and insulin resistance are associated with …

Managing severe chronic pain is a challenging task, given the limited effectiveness of
available pharmacological and non-pharmacological treatments. This issue continues to be …

Simple Summary Cancer stands as a major public health concern worldwide, and a
significant proportion of survivors are affected by recurrent and usually unrelieved cancer …